SCHEMBL9710279

SCHEMBL9710279

CC(=O)Sc1cc(C)c(Cl)cc1C

nearest known ligand 0.36

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CA12 O43570 3/20 0.36
CA1 P00915 3/20 0.36
CA2 P00918 3/20 0.36
CA9 Q16790 3/20 0.36
CA4 P22748 1/20 0.36
CA7 P43166 1/20 0.36
CD44 P16070 1/20 0.35
GRIN2D O15399 1/20 0.34
GRIN3B O60391 1/20 0.34
GRIN1 Q05586 1/20 0.34
GRIN2A Q12879 1/20 0.34
GRIN2B Q13224 1/20 0.34
GRIN2C Q14957 1/20 0.34
GRIN3A Q8TCU5 1/20 0.34
LMNA P02545 3/20 0.33
ALDH1A1 P00352 4/20 0.32
SMN1; SMN2 Q16637 2/20 0.32
MAPK1 P28482 2/20 0.32
GAA P10253 2/20 0.32
KMT2A Q03164 2/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL917173 0.79 ALDH1A1 (0.42) CA1CA2CA9LMNAALDH1A1
SCHEMBL10818701 0.73 CD44 (0.44) CD44GRIN2DGRIN3BGRIN1GRIN2A
SCHEMBL27306895 0.72 CA12 (0.39) CA12CA1CA2CA9CA4
SCHEMBL9167442 0.72 BCAT2 (0.41) CA12CA1CA2CA9ALDH1A1
SCHEMBL27064470 0.72 CD44 (0.42) CD44GRIN2DGRIN3BGRIN1GRIN2A
SCHEMBL18055737 0.69 LMNA (0.42) CA12CA1CA2CA9CA4
SCHEMBL120848 0.69 CD44 (0.61) CD44GRIN2DGRIN3BGRIN1GRIN2A
SCHEMBL2791334 0.68 GPR27 (0.42) CD44GRIN2DGRIN3BGRIN1GRIN2A
SCHEMBL917054 0.68 CYP3A4 (0.46) ALDH1A1SMN1; SMN2GAAKMT2APOLB
SCHEMBL25907608 0.68 IDO1 (0.36) CA12CA1CA2CA9CD44

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-1992021653-A1 PROPENOIC ACID DERIVATIVES SCHERING AGROCHEMICALS LIMITED (GB) 1992-12-10 WO disclosed