Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP11B1 | P15538 | 4/20 | 0.49 |
| ▸ | PDE4A | P27815 | 1/20 | 0.47 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.47 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.47 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.47 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.46 |
| ▸ | CYP11B2 | P19099 | 2/20 | 0.44 |
| ▸ | MEN1 | O00255 | 2/20 | 0.44 |
| ▸ | MAPT | P10636 | 2/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | POLB | P06746 | 2/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.44 |
| ▸ | LMNA | P02545 | 2/20 | 0.44 |
| ▸ | PKM | P14618 | 1/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 1/20 | 0.44 |
| ▸ | IL18 | Q14116 | 1/20 | 0.44 |
| ▸ | PARP15 | Q460N3 | 1/20 | 0.41 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.41 |
| ▸ | PARP2 | Q9UGN5 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8416833 | 0.83 | SLC6A4 (0.53) | CYP11B1PDE4APDE4BPDE4CPDE4D | |
| SCHEMBL10331769 | 0.81 | ESR1 (0.48) | MEN1MAPTKMT2APOLBESR1 | |
| SCHEMBL19280732 | 0.80 | AR (0.52) | PDE4BCYP19A1ARSMN1; SMN2 | |
| SCHEMBL27803879 | 0.80 | SLC6A4 (0.51) | CYP11B1PDE4APDE4BPDE4CPDE4D | |
| SCHEMBL7531116 | 0.79 | ESR1 (0.54) | MEN1MAPTKMT2AESR1ESR2 | |
| SCHEMBL9804483 | 0.79 | CYP11B1 (0.53) | CYP11B1PDE4APDE4BPDE4CPDE4D | |
| SCHEMBL9710713 | 0.78 | AR (0.58) | SLC6A4MAPTLMNAESR1ESR2 | |
| SCHEMBL9710658 | 0.78 | AR (0.42) | CYP11B1CYP11B2MEN1MAPTKMT2A | |
| SCHEMBL7700911 | 0.77 | SLC6A4 (0.62) | CYP11B1PDE4APDE4BPDE4CPDE4D | |
| SCHEMBL9711013 | 0.76 | AR (0.37) | CYP11B1MEN1MAPTKMT2APOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1992018467-A1 | CYANOPHENOXYNAPHTHYL OXYCARBOXYLIC ACID DERIVATIVES | BAYER AKTIENGESELLSCHAFT (DE) | 1992-10-29 | — | — | WO | disclosed |