Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AR | P10275 | 2/20 | 0.37 |
| ▸ | ESR1 | P03372 | 13/20 | 0.36 |
| ▸ | ESR2 | Q92731 | 13/20 | 0.36 |
| ▸ | MEN1 | O00255 | 5/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.36 |
| ▸ | GAA | P10253 | 3/20 | 0.36 |
| ▸ | JAK2 | O60674 | 1/20 | 0.36 |
| ▸ | USP2 | O75604 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.34 |
| ▸ | EGLN2 | Q96KS0 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9710658 | 0.84 | AR (0.42) | ARESR1ESR2MEN1KMT2A | |
| SCHEMBL9710663 | 0.82 | AR (0.37) | ARESR1ESR2MEN1KMT2A | |
| SCHEMBL9314085 | 0.78 | ESR1 (0.37) | ESR1ESR2MEN1KMT2AGAA | |
| SCHEMBL9710755 | 0.76 | CYP11B1 (0.49) | ARESR1ESR2MEN1KMT2A | |
| SCHEMBL27579557 | 0.74 | AR (0.42) | ARESR1ESR2MEN1KMT2A | |
| SCHEMBL9710713 | 0.73 | AR (0.58) | ARESR1ESR2MAPT | |
| SCHEMBL8546460 | 0.73 | MAPT (0.42) | ARMEN1KMT2AGAAMAPT | |
| SCHEMBL9313692 | 0.72 | HSD17B1 (0.36) | ARESR1ESR2MEN1KMT2A | |
| SCHEMBL9710817 | 0.71 | SMN1; SMN2 (0.34) | ARGAASMN1; SMN2NPSR1CYP11B1 | |
| SCHEMBL12316912 | 0.70 | AR (0.43) | ARMEN1KMT2AGAAMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1992018467-A1 | CYANOPHENOXYNAPHTHYL OXYCARBOXYLIC ACID DERIVATIVES | BAYER AKTIENGESELLSCHAFT (DE) | 1992-10-29 | — | — | WO | disclosed |