Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AR | P10275 | 3/20 | 0.58 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.43 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.43 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.43 |
| ▸ | MRGPRX4 | Q96LA9 | 3/20 | 0.43 |
| ▸ | ESRRA | P11474 | 4/20 | 0.41 |
| ▸ | ESR1 | P03372 | 2/20 | 0.41 |
| ▸ | ESR2 | Q92731 | 2/20 | 0.41 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | TTR | P02766 | 1/20 | 0.40 |
| ▸ | PGR | P06401 | 1/20 | 0.40 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.40 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | HSPA5 | P11021 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | CBR1 | P16152 | 1/20 | 0.40 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.40 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9710658 | 0.83 | AR (0.42) | ARESR1ESR2MAPTSLC22A12 | |
| SCHEMBL4181361 | 0.83 | AR (0.65) | ARSLC6A3SLC6A4KCNH2MRGPRX4 | |
| SCHEMBL9563108 | 0.81 | TTR (0.62) | SLC6A3SLC6A4MRGPRX4ESRRAESR1 | |
| SCHEMBL9710755 | 0.78 | CYP11B1 (0.49) | ARSLC6A4ESR1ESR2LMNA | |
| SCHEMBL9710630 | 0.76 | AR (0.50) | ARSLC6A3SLC6A4KCNH2MRGPRX4 | |
| SCHEMBL2985025 | 0.76 | AR (0.56) | ARSLC6A3SLC6A4KCNH2MRGPRX4 | |
| SCHEMBL9644001 | 0.75 | STK39 (0.47) | MRGPRX4ESRRAESR1ESR2HPGD | |
| SCHEMBL11088375 | 0.74 | AR (0.54) | ARSLC6A3SLC6A4KCNH2MRGPRX4 | |
| SCHEMBL8550179 | 0.74 | AR (0.60) | ARSLC6A3SLC6A4KCNH2MRGPRX4 | |
| SCHEMBL3365482 | 0.74 | TTR (0.70) | ARSLC6A3SLC6A4KCNH2MRGPRX4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1992018467-A1 | CYANOPHENOXYNAPHTHYL OXYCARBOXYLIC ACID DERIVATIVES | BAYER AKTIENGESELLSCHAFT (DE) | 1992-10-29 | — | — | WO | disclosed |