Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | GSK3A | P49840 | 1/20 | 0.40 |
| ▸ | GSK3B | P49841 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | AR | P10275 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.38 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.38 |
| ▸ | ELANE | P08246 | 2/20 | 0.37 |
| ▸ | MAPK8 | P45983 | 1/20 | 0.36 |
| ▸ | PGR | P06401 | 1/20 | 0.36 |
| ▸ | MGLL | Q99685 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.35 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.34 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9710635 | 0.90 | ALDH1A1 (0.40) | NPC1GSK3AGSK3BPOLBALDH1A1 | |
| SCHEMBL9710714 | 0.88 | NPC1 (0.49) | NPC1GSK3AGSK3BPOLBALDH1A1 | |
| SCHEMBL9710744 | 0.85 | GSK3A (0.40) | GSK3AGSK3BPOLBMAPTAR | |
| SCHEMBL9710821 | 0.85 | POLB (0.38) | NPC1GSK3AGSK3BPOLBALDH1A1 | |
| SCHEMBL9710718 | 0.82 | L3MBTL1 (0.35) | NPC1GSK3AGSK3BPOLBALDH1A1 | |
| SCHEMBL9710842 | 0.81 | RGS4 (0.50) | POLBALDH1A1ARKMT2AKDM4E | |
| SCHEMBL9710822 | 0.80 | GSK3A (0.50) | GSK3AGSK3BPOLBALDH1A1MAPT | |
| SCHEMBL9711093 | 0.78 | GSK3A (0.37) | GSK3AGSK3BPOLBALDH1A1MAPT | |
| SCHEMBL9710615 | 0.78 | NPC1 (0.48) | NPC1GSK3AGSK3BPOLBALDH1A1 | |
| SCHEMBL9710917 | 0.78 | TDP2 (0.43) | NPC1GSK3AGSK3BPOLBALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1992021662-A1 | POSSIBLY CONDENSED PHENYLIMIDAZOLONES AND PYRIMIDINONES AS HERBICIDES; INTERMEDIATES | DOWELANCO (US) | 1992-12-10 | — | — | WO | disclosed |
| US-5153316-A | Post and preemergence herbicides | DOWELANCO | 1992-10-06 | — | — | US | disclosed |