Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 4/20 | 0.53 |
| ▸ | RAB9A | P51151 | 3/20 | 0.53 |
| ▸ | HPGD | P15428 | 2/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.53 |
| ▸ | NPC1 | O15118 | 1/20 | 0.53 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.47 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.45 |
| ▸ | LMNA | P02545 | 2/20 | 0.44 |
| ▸ | STS | P08842 | 1/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | GLA | P06280 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | ELANE | P08246 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11167581 | 0.95 | RAB9A (0.49) | MAPTRAB9AHPGDSMN1; SMN2NPC1 | |
| SCHEMBL9711125 | 0.85 | NCEH1 (0.45) | MAPTRAB9AHPGDSMN1; SMN2NPC1 | |
| SCHEMBL6553235 | 0.85 | LMNA (0.55) | MAPTRAB9ASMN1; SMN2NPSR1GAA | |
| SCHEMBL11305905 | 0.82 | CA1 (0.56) | MAPTRAB9ASMN1; SMN2L3MBTL1KMT2A | |
| 4-Acetylphenyl Dimethylcarbamate SCHEMBL7185615 | 0.81 | RAB9A (0.76) | MAPTRAB9AHPGDSMN1; SMN2NPC1 | |
| SCHEMBL6885550 | 0.80 | KMT2A (0.53) | RAB9ASMN1; SMN2NPC1L3MBTL1KMT2A | |
| SCHEMBL10793843 | 0.78 | RAB9A (0.43) | MAPTRAB9ASMN1; SMN2NPC1KMT2A | |
| SCHEMBL7754914 | 0.77 | NPSR1 (0.71) | MAPTHPGDSMN1; SMN2NPSR1L3MBTL1 | |
| SCHEMBL9733951 | 0.77 | KMT2A (0.51) | MAPTRAB9AHPGDSMN1; SMN2NPC1 | |
| SCHEMBL11034735 | 0.77 | MAPT (0.57) | MAPTRAB9AHPGDSMN1; SMN2NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 17 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0271307-B1 | METHOD FOR PRODUCING ALKENYLTHIOPHENOLS AND THEIR ESTERS | HOECHST CELANESE CORPORATION (US) | 1992-01-02 | — | — | EP | claimed |
| US-4794205-A | Method for producing alkenylthiophenols and their esters | HOECHST CELANESE CORPORATION (US) | 1988-12-27 | — | — | US | claimed |
| EP-1735275-B1 | ARYL SULFONES AND USES RELATED THERETO | AMGEN INC (US) | 2010-08-18 | — | — | EP | disclosed |
| US-7754890-B2 | Arylsulfones and uses related thereto | AMGEN INC. (US) | 2010-07-13 | — | — | US | disclosed |
| US-7754890-B2 | Arylsulfones and uses related thereto | AMGEN INC. (US) | 2010-07-13 | — | — | US | disclosed |
| US-20080269283-A1 | ARYLSULFONES AND USES RELATED THERETO | AMGEN INC. | 2008-10-30 | — | — | US | disclosed |
| US-20080269283-A1 | ARYLSULFONES AND USES RELATED THERETO | AMGEN INC. | 2008-10-30 | — | — | US | disclosed |
| US-7402704-B2 | Arylsulfones and uses related thereto | AMGEN INC. (US) | 2008-07-22 | — | — | US | disclosed |
| US-7402704-B2 | Arylsulfones and uses related thereto | AMGEN INC. (US) | 2008-07-22 | — | — | US | disclosed |
| US-5151540-A | THIO CARBAMATES AND THEIR DERIVATIVES | HOECHST CELANESE CORPORATION (US) | 1992-09-29 | — | — | US | disclosed |
| US-5151540-A | THIO CARBAMATES AND THEIR DERIVATIVES | HOECHST CELANESE CORPORATION (US) | 1992-09-29 | — | — | US | disclosed |
| EP-0271307-B1 | METHOD FOR PRODUCING ALKENYLTHIOPHENOLS AND THEIR ESTERS | HOECHST CELANESE CORPORATION (US) | 1992-01-02 | — | — | EP | disclosed |
| US-4794205-A | Method for producing alkenylthiophenols and their esters | HOECHST CELANESE CORPORATION (US) | 1988-12-27 | — | — | US | disclosed |
| US-4794205-A | Method for producing alkenylthiophenols and their esters | HOECHST CELANESE CORPORATION (US) | 1988-12-27 | — | — | US | disclosed |
| EP-0271307-A2 | Method for producing alkenylthiophenols and their esters | HOECHST CELANESE CORPORATION (US) | 1988-06-15 | — | — | EP | disclosed |
| EP-0269434-A1 | Method for producing aminothiophenols and their derivatives | HOECHST CELANESE CORPORATION (US) | 1988-06-01 | — | — | EP | disclosed |
| EP-0269434-A1 | Method for producing aminothiophenols and their derivatives | HOECHST CELANESE CORPORATION (US) | 1988-06-01 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080269283-A1 | ARYLSULFONES AND USES RELATED THERETO | ARSA, SULT2A1, UGT2B7 | MAPT 4545/4885RAB9A 2552/4885HPGD 1892/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.