Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 4/20 | 0.55 |
| ▸ | RAB9A | P51151 | 1/20 | 0.52 |
| ▸ | MAPT | P10636 | 4/20 | 0.50 |
| ▸ | POLB | P06746 | 1/20 | 0.50 |
| ▸ | PKM | P14618 | 1/20 | 0.50 |
| ▸ | ELANE | P08246 | 1/20 | 0.48 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.47 |
| ▸ | GAA | P10253 | 2/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 2/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.44 |
| ▸ | TTR | P02766 | 1/20 | 0.44 |
| ▸ | TP53 | P04637 | 1/20 | 0.44 |
| ▸ | GLA | P06280 | 1/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.43 |
| ▸ | ESR1 | P03372 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9711102 | 0.85 | MAPT (0.53) | LMNARAB9AMAPTPOLBELANE | |
| SCHEMBL7754914 | 0.80 | NPSR1 (0.71) | LMNAMAPTHSD17B10GAAALDH1A1 | |
| SCHEMBL11167581 | 0.80 | RAB9A (0.49) | LMNARAB9AMAPTHSD17B10GAA | |
| SCHEMBL269329 | 0.80 | LMNA (0.80) | LMNARAB9AMAPTPOLBPKM | |
| SCHEMBL11305905 | 0.78 | CA1 (0.56) | LMNARAB9AMAPTPOLBPKM | |
| SCHEMBL14760365 | 0.78 | LMNA (0.76) | LMNARAB9AMAPTPOLBPKM | |
| Lithium SCHEMBL30522746 | 0.78 | LMNA (0.76) | LMNARAB9AMAPTPOLBPKM | |
| SCHEMBL5155573 | 0.78 | RAB9A (0.43) | LMNARAB9AMAPTPKMGAA | |
| SCHEMBL9320116 | 0.77 | ALDH1A1 (0.48) | LMNARAB9AMAPTALDH1A1KMT2A | |
| SCHEMBL7781426 | 0.77 | MAPT (0.46) | LMNARAB9AMAPTPKMALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1389185-A2 | AMINOALCOHOL DERIVATIVES | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2004-02-18 | — | — | EP | disclosed |
| WO-2002094770-A2 | AMINOALCOHOL DERIVATIVES | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2002-11-28 | — | — | WO | disclosed |