SCHEMBL9711134

SCHEMBL9711134

C=CSc1ccc(OC(C)=O)cc1

nearest known ligand 0.52

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
LMNA P02545 4/20 0.52
MAPT P10636 3/20 0.47
POLB P06746 1/20 0.47
PKM P14618 1/20 0.47
MEN1 O00255 2/20 0.46
KMT2A Q03164 2/20 0.46
SMN1; SMN2 Q16637 2/20 0.46
KDM4E B2RXH2 2/20 0.46
CYP3A4 P08684 2/20 0.46
TTR P02766 1/20 0.46
TP53 P04637 1/20 0.46
ELANE P08246 1/20 0.46
HSD17B10 Q99714 2/20 0.44
ALDH1A1 P00352 2/20 0.43
GAA P10253 2/20 0.43
HSP90AA1 P07900 1/20 0.43
GLA P06280 1/20 0.41
TSHR P16473 1/20 0.40
HTT P42858 1/20 0.40
ESR1 P03372 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL24171804 0.79 THRB (0.50) LMNAMAPTPOLBPKMMEN1
SCHEMBL5355347 0.78 LMNA (0.61) LMNAMAPTPOLBPKMMEN1
SCHEMBL942837 0.78 LMNA (0.61) LMNAMAPTPOLBPKMMEN1
SCHEMBL1088897 0.77 MAPT (0.50) LMNAMAPTPOLBPKMMEN1
SCHEMBL4729846 0.77 LMNA (0.47) LMNAMAPTPOLBPKMMEN1
SCHEMBL269329 0.77 LMNA (0.80) LMNAMAPTPOLBPKMMEN1
SCHEMBL7998412 0.76 LMNA (0.59) LMNAMAPTPOLBPKMMEN1
SCHEMBL28705673 0.76 THRB (0.59) LMNAMAPTPOLBPKMMEN1
Lithium SCHEMBL30522746 0.75 LMNA (0.76) LMNAMAPTPOLBPKMMEN1
SCHEMBL14760365 0.75 LMNA (0.76) LMNAMAPTPOLBPKMMEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0271307-B1 METHOD FOR PRODUCING ALKENYLTHIOPHENOLS AND THEIR ESTERS HOECHST CELANESE CORPORATION (US) 1992-01-02 EP claimed
US-4794205-A Method for producing alkenylthiophenols and their esters HOECHST CELANESE CORPORATION (US) 1988-12-27 US claimed
EP-0271307-A2 Method for producing alkenylthiophenols and their esters HOECHST CELANESE CORPORATION (US) 1988-06-15 EP claimed
EP-0271307-B1 METHOD FOR PRODUCING ALKENYLTHIOPHENOLS AND THEIR ESTERS HOECHST CELANESE CORPORATION (US) 1992-01-02 EP disclosed
EP-0396413-A2 Copolymers of P-mercaptostyrene and its esters HOECHST CELANESE CORPORATION (US) 1990-11-07 EP disclosed
US-4929694-A COPOLYMERS WITH STYRENE, N-METHYL MALEIMIDE, SEQUESTERING HOECHST CELANESE CORPORATION (US) 1990-05-29 US disclosed
US-4794205-A Method for producing alkenylthiophenols and their esters HOECHST CELANESE CORPORATION (US) 1988-12-27 US disclosed
US-4794205-A Method for producing alkenylthiophenols and their esters HOECHST CELANESE CORPORATION (US) 1988-12-27 US disclosed
EP-0271307-A2 Method for producing alkenylthiophenols and their esters HOECHST CELANESE CORPORATION (US) 1988-06-15 EP disclosed
EP-0271307-A2 Method for producing alkenylthiophenols and their esters HOECHST CELANESE CORPORATION (US) 1988-06-15 EP disclosed