Known targets — ChEMBL curated mechanism
ACHECHKACHRM1CHRM2CHRM3CHRM4CHRM5CHRNA1CHRNB1CHRNDCHRNECHRNGHRH2OPRM1
The experimentally established mechanism targets of Bromide. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE known ✓ | P22303 | 5/20 | 0.48 |
| ▸ | CYP3A4 | P08684 | 4/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.47 |
| ▸ | ALOX15 | P16050 | 4/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.47 |
| ▸ | LMNA | P02545 | 3/20 | 0.47 |
| ▸ | HIF1A | Q16665 | 3/20 | 0.47 |
| ▸ | TYR | P14679 | 2/20 | 0.47 |
| ▸ | HPGD | P15428 | 2/20 | 0.47 |
| ▸ | CA3 | P07451 | 2/20 | 0.47 |
| ▸ | CA14 | Q9ULX7 | 2/20 | 0.47 |
| ▸ | MEN1 | O00255 | 2/20 | 0.47 |
| ▸ | MAPT | P10636 | 2/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.47 |
| ▸ | NPC1 | O15118 | 1/20 | 0.47 |
| ▸ | CA12 | O43570 | 1/20 | 0.47 |
| ▸ | GMNN | O75496 | 1/20 | 0.47 |
| ▸ | CA1 | P00915 | 1/20 | 0.47 |
| ▸ | CA2 | P00918 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1921139 | 0.97 | ACHE (0.50) | ACHECYP3A4HSD17B10ALOX15ALDH1A1 | |
| Iodide SCHEMBL9711185 | 0.94 | APOBEC3A (0.52) | ACHECYP3A4HSD17B10ALOX15ALDH1A1 | |
| Water SCHEMBL11727205 | 0.94 | ACHE (0.48) | ACHECYP3A4HSD17B10ALOX15ALDH1A1 | |
| Hydrochloric Acid SCHEMBL9711148 | 0.94 | ACHE (0.48) | ACHECYP3A4HSD17B10ALOX15ALDH1A1 | |
| SCHEMBL2489383 | 0.80 | APOBEC3A (0.62) | ACHECA12CA9APOBEC3AAPOBEC3G | |
| SCHEMBL23447424 | 0.79 | APP (0.64) | CYP3A4HSD17B10ALOX15ALDH1A1LMNA | |
| Hydrochloric Acid SCHEMBL6368015 | 0.77 | APOBEC3A (0.59) | ACHEALDH1A1KDM4ECA12CA9 | |
| Iodide SCHEMBL6373433 | 0.77 | APOBEC3A (0.69) | ACHECA12CA9APOBEC3AAPOBEC3G | |
| Bromide SCHEMBL8612056 | 0.73 | ACHE (0.50) | ACHEALDH1A1LMNACA1CA2 | |
| Hydroquinone SCHEMBL9857917 | 0.73 | ALOX15 (0.89) | ACHECYP3A4HSD17B10ALOX15ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0267048-B1 | PEROXYACIDS, PHENOXYACETATE PERACID PRECURSORS AND PERHYDROLYSIS SYSTEM | The Clorox Company (US) | 1992-06-03 | — | — | EP | disclosed |
| US-5049305-A | Bleach | ZIELSKE ALFRED G (US) | 1991-09-17 | — | — | US | disclosed |
| US-4956117-A | BLEACHES | THE CLOROX COMPANY (US) | 1990-09-11 | — | — | US | disclosed |
| US-4859800-A | Phenoxyacetate peracid precursors | THE CLOROX COMPANY (US) | 1989-08-22 | — | — | US | disclosed |
| EP-0267048-A2 | Peroxyacids, phenoxyacetate peracid precursors and perhydrolysis system | The Clorox Company (US) | 1988-05-11 | — | — | EP | disclosed |