Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CES2 | O00748 | 2/20 | 0.46 |
| ▸ | HPD | P32754 | 1/20 | 0.41 |
| ▸ | BACE1 | P56817 | 1/20 | 0.36 |
| ▸ | SLC6A9 | P48067 | 3/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
| ▸ | HPGD | P15428 | 2/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.34 |
| ▸ | USP2 | O75604 | 1/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.34 |
| ▸ | FLT1 | P17948 | 1/20 | 0.34 |
| ▸ | FLT4 | P35916 | 1/20 | 0.34 |
| ▸ | KDR | P35968 | 1/20 | 0.34 |
| ▸ | CRBN | Q96SW2 | 1/20 | 0.34 |
| ▸ | SCN4A | P35499 | 1/20 | 0.33 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.33 |
| ▸ | SCN8A | Q9UQD0 | 1/20 | 0.33 |
| ▸ | SCN10A | Q9Y5Y9 | 1/20 | 0.33 |
| ▸ | PSMB11 | A5LHX3 | 1/20 | 0.33 |
| ▸ | PSMA7 | O14818 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9711566 | 0.88 | KMT2A (0.38) | CRBNPGRAR | |
| SCHEMBL9711790 | 0.84 | HPD (0.64) | HPDKDM4EALDH1A1CYP2C19FLT1 | |
| SCHEMBL9711606 | 0.79 | BACE1 (0.39) | CES2BACE1USP2CYP2C19CRBN | |
| SCHEMBL9711573 | 0.78 | CES2 (0.50) | CES2HPDSLC6A9KDM4EALDH1A1 | |
| SCHEMBL9711463 | 0.73 | HPD (0.62) | HPDKDM4EALDH1A1CYP2C19FLT1 | |
| SCHEMBL19295226 | 0.73 | HPD (0.49) | CES2HPDBACE1SLC6A9KDM4E | |
| SCHEMBL9711752 | 0.72 | CES2 (0.43) | CES2HPDSLC6A9KDM4EALDH1A1 | |
| SCHEMBL9711794 | 0.72 | HPD (0.60) | HPDKDM4EALDH1A1CYP2C19FLT1 | |
| SCHEMBL9711670 | 0.71 | HTT (0.31) | — | |
| SCHEMBL19283612 | 0.71 | HPD (0.47) | CES2HPDBACE1SLC6A9KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0170164-B1 | SILVER HALIDE COLOR PHOTOGRAPHIC LIGHT-SENSITIVE MATERIAL | FUJI PHOTO FILM CO., LTD. (JP) | 1988-10-05 | — | — | EP | claimed |
| US-5114461-A | Herbicides | MAY & BAKER LIMITED (GB) | 1992-05-19 | — | — | US | disclosed |
| EP-0278742-A2 | Cyclic diones | MAY & BAKER LIMITED (GB) | 1988-08-17 | — | — | EP | disclosed |