Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CES2 | O00748 | 2/20 | 0.43 |
| ▸ | HPD | P32754 | 1/20 | 0.39 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.38 |
| ▸ | AVPR2 | P30518 | 1/20 | 0.36 |
| ▸ | GPR27 | Q9NS67 | 1/20 | 0.36 |
| ▸ | EDNRB | P24530 | 1/20 | 0.35 |
| ▸ | EDNRA | P25101 | 1/20 | 0.35 |
| ▸ | SLC6A9 | P48067 | 1/20 | 0.35 |
| ▸ | PARP1 | P09874 | 1/20 | 0.35 |
| ▸ | PARP2 | Q9UGN5 | 1/20 | 0.35 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.35 |
| ▸ | LPAR2 | Q9HBW0 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.33 |
| ▸ | POLQ | O75417 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9711591 | 0.89 | MAPT (0.39) | MAPT | |
| SCHEMBL9711657 | 0.88 | MRGPRX4 (0.42) | HPDHDAC11AVPR2GPR27PARP1 | |
| SCHEMBL9711749 | 0.88 | LMNA (0.38) | HDAC11LMNAMAPTSMN1; SMN2ALDH1A1 | |
| SCHEMBL9711506 | 0.85 | HPD (0.61) | HPDLMNAMAPTHTTALDH1A1 | |
| SCHEMBL9711548 | 0.83 | HDAC11 (0.43) | CES2HDAC11PARP1PARP2 | |
| SCHEMBL9711648 | 0.82 | CES2 (0.43) | CES2LMNAMAPTSMN1; SMN2HTT | |
| SCHEMBL9711629 | 0.77 | ALDH1A1 (0.38) | CES2LMNASMN1; SMN2ALDH1A1 | |
| SCHEMBL9711547 | 0.76 | LDHA (0.41) | LMNARXFP1ALDH1A1HPGD | |
| SCHEMBL9711658 | 0.76 | HSD11B1 (0.40) | RXFP1 | |
| SCHEMBL9711573 | 0.76 | CES2 (0.50) | CES2HPDAVPR2GPR27SLC6A9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5114461-A | Herbicides | MAY & BAKER LIMITED (GB) | 1992-05-19 | — | — | US | disclosed |
| EP-0278742-A2 | Cyclic diones | MAY & BAKER LIMITED (GB) | 1988-08-17 | — | — | EP | disclosed |