Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CES2 | O00748 | 2/20 | 0.50 |
| ▸ | HPD | P32754 | 1/20 | 0.47 |
| ▸ | PARP10 | Q53GL7 | 2/20 | 0.41 |
| ▸ | PARP1 | P09874 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | FLT1 | P17948 | 1/20 | 0.37 |
| ▸ | FLT4 | P35916 | 1/20 | 0.37 |
| ▸ | KDR | P35968 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 2/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | CRBN | Q96SW2 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | HPGD | P15428 | 2/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.35 |
| ▸ | USP2 | O75604 | 1/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.35 |
| ▸ | PSEN1 | P49768 | 1/20 | 0.34 |
| ▸ | PSEN2 | P49810 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9711563 | 0.87 | KMT2A (0.38) | CES2HPDPARP10PARP1FLT4 | |
| SCHEMBL9711517 | 0.86 | HPD (0.46) | CES2HPDPARP10PARP1SMN1; SMN2 | |
| SCHEMBL9711769 | 0.83 | MEN1 (0.43) | MEN1KMT2ACYP1A2 | |
| SCHEMBL9711453 | 0.82 | HPD (0.73) | HPDFLT1FLT4KDRMEN1 | |
| SCHEMBL9711702 | 0.80 | BACE1 (0.49) | CES2HPDPARP10PARP1MEN1 | |
| SCHEMBL9711482 | 0.78 | CES2 (0.46) | CES2HPDFLT1FLT4KDR | |
| SCHEMBL9711491 | 0.78 | CES2 (0.49) | CES2PARP10SMN1; SMN2MEN1KMT2A | |
| SCHEMBL9711471 | 0.77 | CES2 (0.43) | CES2HPDPARP10PARP1SMN1; SMN2 | |
| SCHEMBL9711752 | 0.76 | CES2 (0.43) | CES2HPDPARP1SMN1; SMN2KDM4E | |
| SCHEMBL9711583 | 0.70 | SMN1; SMN2 (0.44) | PARP10PARP1SMN1; SMN2MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5114461-A | Herbicides | MAY & BAKER LIMITED (GB) | 1992-05-19 | — | — | US | disclosed |
| EP-0278742-A2 | Cyclic diones | MAY & BAKER LIMITED (GB) | 1988-08-17 | — | — | EP | disclosed |