Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PARP1 | P09874 | 1/20 | 0.36 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.36 |
| ▸ | PARP11 | Q9NR21 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | ITGB1 | P05556 | 1/20 | 0.35 |
| ▸ | ITGA5 | P08648 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
| ▸ | HTT | P42858 | 2/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.34 |
| ▸ | NPC1 | O15118 | 3/20 | 0.34 |
| ▸ | RAB9A | P51151 | 2/20 | 0.34 |
| ▸ | DDB1 | Q16531 | 1/20 | 0.34 |
| ▸ | CRBN | Q96SW2 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9711534 | 0.85 | ITGB1 (0.38) | PARP1PARP10PARP11LMNAITGB1 | |
| SCHEMBL9711494 | 0.73 | SMN1; SMN2 (0.40) | LMNAITGB1ITGA5ALDH1A1MAPT | |
| SCHEMBL9711455 | 0.70 | CES2 (0.42) | ALDH1A1MAPTKMT2A | |
| SCHEMBL9711668 | 0.67 | KDM4E (0.47) | LMNAALDH1A1HTTHSD17B10TDP1 | |
| SCHEMBL9711769 | 0.67 | MEN1 (0.43) | LMNAMEN1KMT2A | |
| SCHEMBL7341520 | 0.66 | P2RX7 (0.33) | LMNAITGB1ITGA5ALDH1A1HTT | |
| SCHEMBL9711486 | 0.66 | ALDH1A1 (0.44) | ALDH1A1HTTTDP1MEN1KMT2A | |
| SCHEMBL10191381 | 0.66 | NPC1 (0.45) | HTTNPC1RAB9A | |
| SCHEMBL9711493 | 0.66 | CYP1A2 (0.49) | LMNAALDH1A1HTTNPC1RAB9A | |
| SCHEMBL13164040 | 0.65 | ALDH1A1 (0.60) | LMNAALDH1A1NPC1RAB9ACRBN |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5114461-A | Herbicides | MAY & BAKER LIMITED (GB) | 1992-05-19 | — | — | US | disclosed |
| EP-0278742-A2 | Cyclic diones | MAY & BAKER LIMITED (GB) | 1988-08-17 | — | — | EP | disclosed |