Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGB1 | P05556 | 1/20 | 0.38 |
| ▸ | ITGA5 | P08648 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.37 |
| ▸ | HTT | P42858 | 2/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
| ▸ | PARP1 | P09874 | 1/20 | 0.36 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.36 |
| ▸ | PARP11 | Q9NR21 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9711518 | 0.85 | PARP1 (0.36) | ITGB1ITGA5ALDH1A1HTTHSD17B10 | |
| SCHEMBL10191381 | 0.79 | NPC1 (0.45) | HTTNPC1RAB9A | |
| SCHEMBL9711668 | 0.78 | KDM4E (0.47) | ALDH1A1HTTHSD17B10TDP1MEN1 | |
| SCHEMBL9711560 | 0.76 | TSHR (0.51) | ALDH1A1TDP1NPC1RAB9AMEN1 | |
| SCHEMBL9711621 | 0.74 | PARP1 (0.42) | ALDH1A1NPC1RAB9APARP1PARP10 | |
| SCHEMBL9711646 | 0.73 | ITGB1 (0.42) | ITGB1ITGA5ALDH1A1HSD17B10MEN1 | |
| SCHEMBL9711583 | 0.71 | SMN1; SMN2 (0.44) | ALDH1A1NPC1RAB9APARP1PARP10 | |
| SCHEMBL9711723 | 0.70 | HPD (0.40) | ALDH1A1NPC1RAB9AMEN1KMT2A | |
| SCHEMBL9711757 | 0.69 | RAB9A (0.44) | ALDH1A1HTTHSD17B10NPC1RAB9A | |
| SCHEMBL9711814 | 0.69 | HPGD (0.41) | ALDH1A1HTTNPC1RAB9AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5114461-A | Herbicides | MAY & BAKER LIMITED (GB) | 1992-05-19 | — | — | US | disclosed |
| EP-0278742-A2 | Cyclic diones | MAY & BAKER LIMITED (GB) | 1988-08-17 | — | — | EP | disclosed |