Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | CASP1 | P29466 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 2/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | ATM | Q13315 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | F7 | P08709 | 1/20 | 0.38 |
| ▸ | PARP1 | P09874 | 1/20 | 0.38 |
| ▸ | F3 | P13726 | 1/20 | 0.38 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.38 |
| ▸ | JAK2 | O60674 | 1/20 | 0.38 |
| ▸ | JAK1 | P23458 | 1/20 | 0.38 |
| ▸ | TYK2 | P29597 | 1/20 | 0.38 |
| ▸ | ERCC5 | P28715 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9711460 | 0.89 | ALDH1A1 (0.44) | TSHRRAB9AMEN1KMT2AATM | |
| SCHEMBL9430443 | 0.87 | SMN1; SMN2 (0.45) | SMN1; SMN2TSHRCASP1RAB9AMEN1 | |
| SCHEMBL9711637 | 0.84 | LMNA (0.32) | RAB9AMEN1KMT2AATML3MBTL1 | |
| SCHEMBL10815118 | 0.83 | SMN1; SMN2 (0.53) | SMN1; SMN2TSHRCASP1RAB9AMEN1 | |
| SCHEMBL9711517 | 0.83 | HPD (0.46) | SMN1; SMN2MEN1KMT2AALDH1A1KDM4E | |
| SCHEMBL9711455 | 0.82 | CES2 (0.42) | KMT2AALDH1A1MAPT | |
| SCHEMBL9711516 | 0.82 | HPD (0.48) | SMN1; SMN2RAB9AMEN1KMT2AALDH1A1 | |
| SCHEMBL9711451 | 0.82 | LMNA (0.42) | RAB9AMEN1KMT2AALDH1A1MAPT | |
| SCHEMBL9711472 | 0.81 | NOTUM (0.36) | SLC6A2SLC6A4 | |
| SCHEMBL7344969 | 0.80 | TSHR (0.50) | SMN1; SMN2TSHRCASP1ALDH1A1MAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5114461-A | Herbicides | MAY & BAKER LIMITED (GB) | 1992-05-19 | — | — | US | disclosed |
| EP-0278742-A2 | Cyclic diones | MAY & BAKER LIMITED (GB) | 1988-08-17 | — | — | EP | disclosed |