Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 6/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.44 |
| ▸ | PPARG | P37231 | 2/20 | 0.44 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.44 |
| ▸ | PPARA | Q07869 | 1/20 | 0.44 |
| ▸ | RORC | P51449 | 4/20 | 0.43 |
| ▸ | LMNA | P02545 | 3/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.43 |
| ▸ | MAPT | P10636 | 2/20 | 0.43 |
| ▸ | MEN1 | O00255 | 2/20 | 0.43 |
| ▸ | TP53 | P04637 | 1/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.43 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.43 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.43 |
| ▸ | PKM | P14618 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.43 |
| ▸ | THPO | P40225 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9711456 | 0.85 | ALDH1A1 (0.41) | SMN1; SMN2CYP3A4RORCLMNAKMT2A | |
| SCHEMBL9711540 | 0.84 | HPD (0.49) | SMN1; SMN2CYP3A4MAPK1LMNAKMT2A | |
| SCHEMBL9711477 | 0.80 | HPD (0.42) | SMN1; SMN2LMNAKMT2AMAPTMEN1 | |
| SCHEMBL9711632 | 0.79 | CES1 (0.45) | MAPK1MAPTTSHRALDH1A1 | |
| SCHEMBL9711516 | 0.78 | HPD (0.48) | SMN1; SMN2CYP3A4LMNAKMT2AMAPT | |
| SCHEMBL9711489 | 0.78 | CES2 (0.50) | LMNAKMT2AMAPTMEN1TP53 | |
| SCHEMBL9711723 | 0.77 | HPD (0.40) | LMNAKMT2AMAPTMEN1PKM | |
| SCHEMBL9711455 | 0.76 | CES2 (0.42) | KMT2AMAPTALDH1A1 | |
| SCHEMBL9711486 | 0.74 | ALDH1A1 (0.44) | SMN1; SMN2KMT2AMEN1HTTALDH1A1 | |
| SCHEMBL9711583 | 0.74 | SMN1; SMN2 (0.44) | SMN1; SMN2MAPK1KMT2AMAPTMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5114461-A | Herbicides | MAY & BAKER LIMITED (GB) | 1992-05-19 | — | — | US | disclosed |
| EP-0278742-A2 | Cyclic diones | MAY & BAKER LIMITED (GB) | 1988-08-17 | — | — | EP | disclosed |