SCHEMBL9712055

SCHEMBL9712055

COSC(O)c1ccccc1

nearest known ligand 0.42

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CHRM2 P08172 2/20 0.42
CHRM1 P11229 1/20 0.42
CHRM3 P20309 1/20 0.42
KMT2A Q03164 2/20 0.42
LMNA P02545 4/20 0.41
ADRA2C P18825 2/20 0.40
KDM4E B2RXH2 2/20 0.40
ADRA2A P08913 1/20 0.40
HIF1A Q16665 1/20 0.40
ALDH1A1 P00352 2/20 0.39
MAPK1 P28482 1/20 0.38
TSHR P16473 2/20 0.38
ADRA1A P35348 1/20 0.38
AOC3 Q16853 1/20 0.38
RGS12 O14924 1/20 0.38
GLA P06280 1/20 0.38
CYP3A4 P08684 1/20 0.38
CYP2D6 P10635 1/20 0.38
CYP2C9 P11712 1/20 0.38
PKM P14618 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3718532 0.81 LMNA (0.41) CHRM2CHRM1CHRM3LMNAADRA2C
SCHEMBL9574273 0.76 KMT2A (0.40) KMT2ALMNAALDH1A1TSHRHTR2A
SCHEMBL22519675 0.73 LMNA (0.46) CHRM2KMT2ALMNAADRA2CKDM4E
SCHEMBL1268813 0.73 LMNA (0.46) CHRM2KMT2ALMNAADRA2CKDM4E
SCHEMBL3648024 0.72 ALDH1A1 (0.46) KMT2ALMNAADRA2CKDM4EADRA2A
SCHEMBL28106402 0.71 LMNA (0.44) CHRM2KMT2ALMNAADRA2CKDM4E
SCHEMBL9633963 0.70 TSHR (0.46) LMNAADRA2CKDM4EADRA2AHIF1A
Diphenylmethanol SCHEMBL11867320 0.70 SMN1; SMN2 (0.52) KMT2ALMNAADRA2CKDM4EADRA2A
SCHEMBL6076547 0.70 LMNA (0.43) CHRM2KMT2ALMNAADRA2CKDM4E
SCHEMBL619133 0.69 KMT2A (0.46) CHRM2KMT2ALMNAADRA2CKDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0309839-B1 PROCESS FOR THE PREPARATION OF OXYETHYL MERCAPTOBENZALDEHYDES, AND THEIR OXIDATION PRODUCTS HOECHST AKTIENGESELLSCHAFT (DE) 1992-03-04 EP disclosed
US-4922014-A Process for the preparation of oxethylmercaptobenzaldehydes and their oxidation products HOECHST AKTIENGESELLSCHAFT (DE) 1990-05-01 US disclosed
EP-0309839-A1 Process for the preparation of oxyethyl mercaptobenzaldehydes, and their oxidation products HOECHST AKTIENGESELLSCHAFT (DE) 1989-04-05 EP disclosed