Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOTUM | Q6P988 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.38 |
| ▸ | SHMT2 | P34897 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 2/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | GPBAR1 | Q8TDU6 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 2/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | THRB | P10828 | 1/20 | 0.35 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | NPC1 | O15118 | 2/20 | 0.34 |
| ▸ | RAB9A | P51151 | 2/20 | 0.34 |
| ▸ | PGR | P06401 | 1/20 | 0.34 |
| ▸ | PPARG | P37231 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9285642 | 0.83 | ALDH1A1 (0.45) | NOTUMALDH1A1LMNAHPGDSMN1; SMN2 | |
| SCHEMBL9272515 | 0.81 | NOTUM (0.44) | NOTUMALDH1A1KDM4ELMNASMN1; SMN2 | |
| SCHEMBL9712333 | 0.74 | ALDH1A1 (0.49) | ALDH1A1KDM4EGAALMNAL3MBTL1 | |
| SCHEMBL9197584 | 0.73 | ALDH1A1 (0.47) | ALDH1A1KDM4EL3MBTL1MEN1KMT2A | |
| SCHEMBL9392502 | 0.71 | ALDH1A1 (0.48) | NOTUMALDH1A1HPGDSMN1; SMN2KMT2A | |
| SCHEMBL15154503 | 0.70 | MEN1 (0.59) | ALDH1A1KDM4ELMNAHPGDSMN1; SMN2 | |
| SCHEMBL9195565 | 0.70 | ALDH1A1 (0.43) | ALDH1A1KDM4EGAALMNAL3MBTL1 | |
| SCHEMBL9202310 | 0.70 | MEN1 (0.71) | ALDH1A1KDM4ELMNAL3MBTL1MEN1 | |
| SCHEMBL9394558 | 0.69 | SPR (0.54) | ALDH1A1HPGDSMN1; SMN2MEN1KMT2A | |
| SCHEMBL9393900 | 0.69 | TSHR (0.52) | ALDH1A1GAAHPGDSMN1; SMN2MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1992018483-A1 | QUINOLINE DERIVATIVES | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1992-10-29 | — | — | WO | disclosed |