SCHEMBL9712347

SCHEMBL9712347

O=[C]c1c(F)cc(Cl)cc1F

nearest known ligand 0.35

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
TSHR P16473 1/20 0.35
TRPV4 Q9HBA0 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL95722 0.78 CES2 (0.37) TRPV4
SCHEMBL2951474 0.74 TRPV4 (0.31) TRPV4
SCHEMBL31308688 0.74 TSHR (0.35) TSHRTRPV4
SCHEMBL566436 0.74 SELL (0.32) TRPV4
SCHEMBL14677092 0.74 TRPV4 (0.58) TSHRTRPV4
SCHEMBL9712517 0.73 CES2 (0.31)
SCHEMBL94929 0.72 ALDH1A1 (0.45) TSHR
SCHEMBL7703149 0.71 CES2 (0.31)
SCHEMBL10701289 0.70 MAPK1 (0.33)
SCHEMBL11593707 0.70 TSHR (0.37) TSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5117057-A Insecticidal N' substituted-N-N'-disubstituted-hydrazines ROHM AND HAAS COMPANY (US) 1992-05-26 US disclosed