SCHEMBL9712380

SCHEMBL9712380

Cc1cccc(C(=O)c2ccccc2Cl)c1C(=O)Cl

nearest known ligand 0.50

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 3/20 0.50
LMNA P02545 1/20 0.47
GAA P10253 1/20 0.47
CES2 O00748 1/20 0.46
CES1 P23141 1/20 0.46
RECQL P46063 1/20 0.45
MAPK13 O15264 3/20 0.44
MAPK12 P53778 3/20 0.44
MAPK11 Q15759 3/20 0.44
MAPK14 Q16539 3/20 0.44
KMT2A Q03164 3/20 0.44
CYP3A4 P08684 1/20 0.42
CYP2C9 P11712 1/20 0.42
POLB P06746 1/20 0.42
MAPT P10636 1/20 0.41
RORB Q92753 2/20 0.40
MEN1 O00255 1/20 0.40
RORC P51449 1/20 0.40
FABP3 P05413 1/20 0.40
FABP4 P15090 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Hydrochloric Acid SCHEMBL8174910 0.88 ALDH1A1 (0.41) ALDH1A1LMNAGAARECQLMAPK13
SCHEMBL9712387 0.87 ALDH1A1 (0.50) ALDH1A1LMNAGAACES2CES1
SCHEMBL14528312 0.82 MAPK13 (0.59) ALDH1A1LMNAGAACES2CES1
SCHEMBL11606192 0.81 ALDH1A1 (0.43) ALDH1A1LMNAGAACES2CES1
SCHEMBL476833 0.80 ALDH1A1 (0.71) ALDH1A1LMNAKMT2AFABP3FABP4
SCHEMBL301550 0.80 ALDH1A1 (0.46) ALDH1A1LMNAKMT2ACYP3A4CYP2C9
SCHEMBL31611275 0.80 ALDH1A1 (0.46) ALDH1A1LMNAKMT2ACYP3A4CYP2C9
SCHEMBL29399311 0.78 CES2 (0.71) ALDH1A1LMNAGAACES2CES1
SCHEMBL50416 0.78 CES2 (0.71) ALDH1A1LMNAGAACES2CES1
O-Xylene SCHEMBL27624725 0.77 CES2 (0.54) ALDH1A1CES2CES1KMT2APOLB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5117057-A Insecticidal N' substituted-N-N'-disubstituted-hydrazines ROHM AND HAAS COMPANY (US) 1992-05-26 US disclosed