SCHEMBL9712387

SCHEMBL9712387

Cc1cccc(C(=O)Cl)c1C(=O)c1ccccc1Cl

nearest known ligand 0.50

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 3/20 0.50
LMNA P02545 1/20 0.50
GAA P10253 1/20 0.50
CES2 O00748 1/20 0.46
CES1 P23141 1/20 0.46
KMT2A Q03164 2/20 0.44
POLB P06746 1/20 0.42
CYP2C9 P11712 1/20 0.41
RORC P51449 1/20 0.41
RECQL P46063 1/20 0.41
MAPK13 O15264 2/20 0.41
MAPK12 P53778 2/20 0.41
MAPK11 Q15759 2/20 0.41
MAPK14 Q16539 2/20 0.41
MAPT P10636 1/20 0.41
MEN1 O00255 1/20 0.40
FABP3 P05413 1/20 0.40
FABP4 P15090 1/20 0.40
TP53 P04637 1/20 0.40
HPGD P15428 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Hydrochloric Acid SCHEMBL8178571 0.88 ALDH1A1 (0.44) ALDH1A1LMNAGAAKMT2APOLB
SCHEMBL9712380 0.87 ALDH1A1 (0.50) ALDH1A1LMNAGAACES2CES1
SCHEMBL27321464 0.83 AKR1C3 (0.46) ALDH1A1LMNAGAAKMT2APOLB
SCHEMBL9712609 0.82 ALDH1A1 (0.59) ALDH1A1LMNAGAACES2CES1
SCHEMBL9712460 0.81 BCL2L1 (0.51) ALDH1A1KMT2AMAPTMEN1HPGD
O-Xylene SCHEMBL27624725 0.80 CES2 (0.54) ALDH1A1CES2CES1KMT2APOLB
SCHEMBL31611275 0.80 ALDH1A1 (0.46) ALDH1A1LMNAKMT2APOLBCYP2C9
SCHEMBL301550 0.80 ALDH1A1 (0.46) ALDH1A1LMNAKMT2APOLBCYP2C9
SCHEMBL9712456 0.80 GABRA1 (0.42) ALDH1A1KMT2APOLBCYP2C9RORC
SCHEMBL14528312 0.78 MAPK13 (0.59) ALDH1A1LMNAGAACES2CES1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5117057-A Insecticidal N' substituted-N-N'-disubstituted-hydrazines ROHM AND HAAS COMPANY (US) 1992-05-26 US disclosed