Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.39 |
| ▸ | PLK1 | P53350 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 2/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | HDAC3 | O15379 | 3/20 | 0.34 |
| ▸ | HDAC4 | P56524 | 3/20 | 0.34 |
| ▸ | HDAC1 | Q13547 | 3/20 | 0.34 |
| ▸ | HDAC7 | Q8WUI4 | 3/20 | 0.34 |
| ▸ | HDAC2 | Q92769 | 3/20 | 0.34 |
| ▸ | HDAC10 | Q969S8 | 3/20 | 0.34 |
| ▸ | HDAC11 | Q96DB2 | 3/20 | 0.34 |
| ▸ | HDAC8 | Q9BY41 | 3/20 | 0.34 |
| ▸ | HDAC6 | Q9UBN7 | 3/20 | 0.34 |
| ▸ | HDAC9 | Q9UKV0 | 3/20 | 0.34 |
| ▸ | HDAC5 | Q9UQL6 | 3/20 | 0.34 |
| ▸ | GAA | P10253 | 4/20 | 0.34 |
| ▸ | THRB | P10828 | 3/20 | 0.34 |
| ▸ | NPC1 | O15118 | 2/20 | 0.34 |
| ▸ | CNR1 | P21554 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10767768 | 0.86 | CA1 (0.38) | — | |
| SCHEMBL8416074 | 0.83 | ALDH1A1 (0.33) | ALDH1A1TDP1TAS1R3TAS1R1 | |
| SCHEMBL9712569 | 0.79 | SMN1; SMN2 (0.44) | ALDH1A1PLK1MAPTHTTSMN1; SMN2 | |
| SCHEMBL9712330 | 0.72 | PLK1 (0.41) | ALDH1A1PLK1MAPTHTTSMN1; SMN2 | |
| SCHEMBL9712502 | 0.72 | PLK1 (0.41) | ALDH1A1PLK1MAPTHTTSMN1; SMN2 | |
| SCHEMBL9712357 | 0.72 | HTT (0.43) | ALDH1A1PLK1MAPTHTTSMN1; SMN2 | |
| SCHEMBL28595340 | 0.69 | NPC1 (0.53) | PLK1MAPTSMN1; SMN2HDAC3HDAC4 | |
| SCHEMBL9712448 | 0.68 | MAPT (0.40) | ALDH1A1PLK1MAPTHTTSMN1; SMN2 | |
| SCHEMBL2935942 | 0.68 | ALDH1A1 (0.70) | ALDH1A1PLK1MAPTHTTSMN1; SMN2 | |
| SCHEMBL11860196 | 0.67 | ALDH1A1 (0.35) | ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5117057-A | Insecticidal N' substituted-N-N'-disubstituted-hydrazines | ROHM AND HAAS COMPANY (US) | 1992-05-26 | — | — | US | disclosed |