Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.44 |
| ▸ | HTT | P42858 | 2/20 | 0.44 |
| ▸ | MAPT | P10636 | 2/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.42 |
| ▸ | NPC1 | O15118 | 3/20 | 0.40 |
| ▸ | RAB9A | P51151 | 2/20 | 0.40 |
| ▸ | PLK1 | P53350 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 5/20 | 0.36 |
| ▸ | CNR1 | P21554 | 1/20 | 0.36 |
| ▸ | CNR2 | P34972 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 2/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | AGTR1 | P30556 | 1/20 | 0.35 |
| ▸ | TAS2R14 | Q9NYV8 | 1/20 | 0.35 |
| ▸ | TTR | P02766 | 1/20 | 0.34 |
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.34 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.34 |
| ▸ | BCL2 | P10415 | 1/20 | 0.34 |
| ▸ | RXRA | P19793 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9712357 | 0.81 | HTT (0.43) | SMN1; SMN2HTTMAPTALDH1A1NPC1 | |
| SCHEMBL9712394 | 0.79 | ALDH1A1 (0.39) | SMN1; SMN2HTTMAPTALDH1A1NPC1 | |
| SCHEMBL9712330 | 0.75 | PLK1 (0.41) | SMN1; SMN2HTTMAPTALDH1A1NPC1 | |
| SCHEMBL9712502 | 0.75 | PLK1 (0.41) | SMN1; SMN2HTTMAPTALDH1A1NPC1 | |
| SCHEMBL21362751 | 0.73 | ALDH1A1 (0.60) | SMN1; SMN2HTTMAPTALDH1A1NPC1 | |
| SCHEMBL9712448 | 0.71 | MAPT (0.40) | SMN1; SMN2HTTMAPTALDH1A1NPC1 | |
| SCHEMBL2935942 | 0.71 | ALDH1A1 (0.70) | SMN1; SMN2HTTMAPTALDH1A1NPC1 | |
| SCHEMBL28400194 | 0.70 | HTT (0.67) | SMN1; SMN2HTTMAPTALDH1A1RAB9A | |
| SCHEMBL9712581 | 0.69 | PLK1 (0.44) | SMN1; SMN2HTTMAPTALDH1A1NPC1 | |
| SCHEMBL28610788 | 0.69 | GAA (0.56) | SMN1; SMN2MAPTALDH1A1NPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5117057-A | Insecticidal N' substituted-N-N'-disubstituted-hydrazines | ROHM AND HAAS COMPANY (US) | 1992-05-26 | — | — | US | disclosed |