Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PLK1 | P53350 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.41 |
| ▸ | GAA | P10253 | 3/20 | 0.41 |
| ▸ | RAB9A | P51151 | 3/20 | 0.41 |
| ▸ | NPC1 | O15118 | 2/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.40 |
| ▸ | MAPT | P10636 | 3/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | TP53 | P04637 | 1/20 | 0.37 |
| ▸ | THRB | P10828 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | PPARG | P37231 | 1/20 | 0.36 |
| ▸ | LTC4S | Q16873 | 1/20 | 0.35 |
| ▸ | CNR1 | P21554 | 1/20 | 0.35 |
| ▸ | CNR2 | P34972 | 1/20 | 0.35 |
| ▸ | HRH2 | P25021 | 1/20 | 0.34 |
| ▸ | HRH1 | P35367 | 1/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9712357 | 0.83 | HTT (0.43) | PLK1ALDH1A1GAARAB9ANPC1 | |
| SCHEMBL9712330 | 0.83 | PLK1 (0.41) | PLK1ALDH1A1GAARAB9ANPC1 | |
| SCHEMBL525385 | 0.82 | AKR1C3 (0.48) | ALDH1A1GAAMAPTMEN1KMT2A | |
| SCHEMBL9712504 | 0.81 | NR4A1 (0.50) | ALDH1A1RAB9AMAPTMEN1KMT2A | |
| SCHEMBL9712448 | 0.79 | MAPT (0.40) | PLK1ALDH1A1GAANPC1LMNA | |
| SCHEMBL9712569 | 0.75 | SMN1; SMN2 (0.44) | PLK1ALDH1A1GAARAB9ANPC1 | |
| SCHEMBL9712581 | 0.74 | PLK1 (0.44) | PLK1ALDH1A1GAARAB9ANPC1 | |
| SCHEMBL9712508 | 0.72 | GAA (0.49) | PLK1ALDH1A1GAARAB9ANPC1 | |
| SCHEMBL9712394 | 0.72 | ALDH1A1 (0.39) | PLK1ALDH1A1GAARAB9ANPC1 | |
| SCHEMBL9029744 | 0.72 | ALDH1A1 (0.42) | PLK1ALDH1A1RAB9ANPC1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5117057-A | Insecticidal N' substituted-N-N'-disubstituted-hydrazines | ROHM AND HAAS COMPANY (US) | 1992-05-26 | — | — | US | disclosed |