Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 9/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 8/20 | 0.40 |
| ▸ | MEN1 | O00255 | 7/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.40 |
| ▸ | PLK1 | P53350 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.37 |
| ▸ | LMNA | P02545 | 6/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.37 |
| ▸ | HTT | P42858 | 4/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | MITF | O75030 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 2/20 | 0.34 |
| ▸ | ALPG | P10696 | 1/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
| ▸ | HNF4A | P41235 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5082416 | 0.83 | TTR (0.41) | MAPTKMT2AMEN1MAPK1ALDH1A1 | |
| SCHEMBL9712502 | 0.79 | PLK1 (0.41) | MAPTKMT2AMEN1PLK1ALDH1A1 | |
| SCHEMBL9712357 | 0.79 | HTT (0.43) | MAPTKMT2AMEN1PLK1ALDH1A1 | |
| SCHEMBL9712330 | 0.79 | PLK1 (0.41) | MAPTKMT2AMEN1PLK1ALDH1A1 | |
| SCHEMBL9712479 | 0.75 | SMN1; SMN2 (0.46) | MAPTKMT2AMEN1MAPK1ALDH1A1 | |
| SCHEMBL6212223 | 0.74 | ALDH1A1 (0.47) | MAPTALDH1A1SMN1; SMN2HTTTDP1 | |
| SCHEMBL2355479 | 0.73 | LMNA (0.47) | MAPTKMT2AMEN1MAPK1ALDH1A1 | |
| SCHEMBL9712499 | 0.73 | MAPT (0.46) | MAPTKMT2AMEN1MAPK1ALDH1A1 | |
| SCHEMBL9712669 | 0.73 | NPSR1 (0.35) | MAPTKMT2AMEN1ALDH1A1LMNA | |
| SCHEMBL27907988 | 0.72 | AKR1C3 (0.43) | MAPTKMT2AMEN1MAPK1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5117057-A | Insecticidal N' substituted-N-N'-disubstituted-hydrazines | ROHM AND HAAS COMPANY (US) | 1992-05-26 | — | — | US | disclosed |