Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.35 |
| ▸ | MGLL | Q99685 | 1/20 | 0.34 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.34 |
| ▸ | TNK2 | Q07912 | 3/20 | 0.34 |
| ▸ | DHFR | P00374 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.32 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7272729 | 0.91 | MEN1 (0.39) | MEN1KMT2ANPC1RAB9AHSD11B1 | |
| SCHEMBL7272735 | 0.91 | MEN1 (0.39) | MEN1KMT2ANPC1RAB9AHSD11B1 | |
| SCHEMBL3329236 | 0.85 | APP (0.43) | MEN1KMT2ANPC1RAB9AHSD11B1 | |
| SCHEMBL7284022 | 0.83 | MEN1 (0.38) | MEN1KMT2ANPC1RAB9AHSD11B1 | |
| SCHEMBL7285049 | 0.81 | ALDH1A1 (0.42) | MEN1KMT2ANPC1RAB9AHSD11B1 | |
| SCHEMBL7285052 | 0.81 | ALDH1A1 (0.42) | MEN1KMT2ANPC1RAB9AHSD11B1 | |
| SCHEMBL7281392 | 0.78 | MGLL (0.43) | MEN1KMT2ANPC1RAB9AMGLL | |
| SCHEMBL1070597 | 0.78 | MEN1 (0.51) | MEN1KMT2AHPGD | |
| SCHEMBL1070599 | 0.78 | MEN1 (0.51) | MEN1KMT2AHPGD | |
| SCHEMBL3500438 | 0.77 | TNK2 (0.44) | MEN1KMT2ANPC1RAB9AHSD11B1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5137889-A | Hypotensive agents; coronary vasodilators; calcium antagonists; antiinflammatory agents | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1992-08-11 | — | — | US | disclosed |