Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.46 |
| ▸ | LMNA | P02545 | 4/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.46 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 6/20 | 0.42 |
| ▸ | HTT | P42858 | 2/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | TP53 | P04637 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | SRD5A2 | P31213 | 2/20 | 0.41 |
| ▸ | THRB | P10828 | 1/20 | 0.39 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL363400 | 0.87 | ALDH1A1 (0.52) | ALDH1A1LMNASMN1; SMN2AKR1C3MAPT | |
| SCHEMBL9712369 | 0.84 | MDM2 (0.47) | LMNAMAPTHTTKMT2ATP53 | |
| SCHEMBL1630082 | 0.80 | CES2 (0.55) | ALDH1A1LMNASMN1; SMN2TDP1AKR1C3 | |
| SCHEMBL2436576 | 0.79 | CES2 (0.50) | LMNASMN1; SMN2MAPTHTTKMT2A | |
| SCHEMBL8845805 | 0.78 | LMNA (0.54) | ALDH1A1LMNASMN1; SMN2TDP1AKR1C3 | |
| SCHEMBL9712382 | 0.78 | RAB9A (0.48) | ALDH1A1LMNAMAPTHTTKMT2A | |
| SCHEMBL4376001 | 0.78 | POLB (0.49) | LMNASMN1; SMN2AKR1C3MAPTHTT | |
| SCHEMBL7673359 | 0.77 | AKR1C3 (0.61) | ALDH1A1LMNASMN1; SMN2TDP1AKR1C3 | |
| SCHEMBL9490579 | 0.76 | MAPT (0.53) | ALDH1A1LMNASMN1; SMN2MAPTHTT | |
| SCHEMBL8611329 | 0.74 | NPC1 (0.53) | ALDH1A1LMNASMN1; SMN2TDP1AKR1C3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5117057-A | Insecticidal N' substituted-N-N'-disubstituted-hydrazines | ROHM AND HAAS COMPANY (US) | 1992-05-26 | — | — | US | disclosed |