Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRM5 | P41594 | 10/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.43 |
| ▸ | GLA | P06280 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.43 |
| ▸ | ALDH1A3 | P47895 | 5/20 | 0.42 |
| ▸ | ALDH1A2 | O94788 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 2/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.39 |
| ▸ | PAK4 | O96013 | 1/20 | 0.39 |
| ▸ | CSF1R | P07333 | 1/20 | 0.39 |
| ▸ | RET | P07949 | 1/20 | 0.39 |
| ▸ | GRK5 | P34947 | 1/20 | 0.39 |
| ▸ | MAPK8 | P45983 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL785129 | 0.81 | ALDH1A3 (0.67) | ALDH1A1KDM4EHPGDHSD17B10ALDH1A3 | |
| SCHEMBL13454312 | 0.81 | ALDH1A3 (0.65) | ALDH1A1KDM4EHPGDHSD17B10ALDH1A3 | |
| SCHEMBL970705 | 0.81 | ALDH1A1 (0.62) | ALDH1A1KDM4EGLAHPGDHSD17B10 | |
| SCHEMBL971706 | 0.80 | ALDH1A3 (0.63) | ALDH1A1KDM4EHPGDHSD17B10ALDH1A3 | |
| SCHEMBL18288722 | 0.79 | ALDH1A3 (0.67) | ALDH1A1KDM4EHPGDHSD17B10ALDH1A3 | |
| SCHEMBL18288730 | 0.79 | ALDH1A3 (0.67) | ALDH1A1KDM4EHPGDHSD17B10ALDH1A3 | |
| SCHEMBL972538 | 0.79 | ALDH1A3 (0.61) | ALDH1A1KDM4EHPGDHSD17B10ALDH1A3 | |
| SCHEMBL785197 | 0.79 | ALDH1A3 (0.46) | ALDH1A1KDM4EHPGDHSD17B10ALDH1A3 | |
| SCHEMBL13454279 | 0.77 | SCD (0.50) | ALDH1A1KDM4EHPGDALDH1A3ALDH1A2 | |
| SCHEMBL10353295 | 0.77 | ALDH1A1 (0.56) | ALDH1A1KDM4EGLAHPGDHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7867629-B2 | Nitrogenous heterocyclic derivative and organic electroluminescent element employing the same | IDEMITSU KOSAN CO., LTD. (JP) | 2011-01-11 | — | — | US | disclosed |