Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTPN1 | P18031 | 1/20 | 0.46 |
| ▸ | ACHE | P22303 | 1/20 | 0.41 |
| ▸ | BACE1 | P56817 | 1/20 | 0.41 |
| ▸ | PPARG | P37231 | 1/20 | 0.36 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.35 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.35 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.35 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.35 |
| ▸ | GABRA3 | P34903 | 1/20 | 0.35 |
| ▸ | GABRA2 | P47869 | 1/20 | 0.35 |
| ▸ | GABRA6 | Q16445 | 1/20 | 0.35 |
| ▸ | HSP90AA1 | P07900 | 2/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | ATM | Q13315 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15732985 | 0.81 | PTPN1 (0.63) | PTPN1ACHEBACE1S100A4STAT3 | |
| SCHEMBL15732974 | 0.81 | PTPN1 (0.63) | PTPN1ACHEBACE1S100A4STAT3 | |
| SCHEMBL15733081 | 0.81 | PTPN1 (0.63) | PTPN1ACHEBACE1S100A4STAT3 | |
| SCHEMBL15732809 | 0.81 | PTPN1 (0.63) | PTPN1ACHEBACE1S100A4STAT3 | |
| SCHEMBL15732933 | 0.81 | PTPN1 (0.63) | PTPN1ACHEBACE1S100A4STAT3 | |
| SCHEMBL15732842 | 0.80 | PTPN1 (0.60) | PTPN1ACHEBACE1S100A4CNR1 | |
| SCHEMBL10503501 | 0.77 | S100A4 (0.42) | GABRA1GABRG2GABRB3GABRA5GABRA3 | |
| SCHEMBL15733045 | 0.75 | PTPN1 (0.54) | PTPN1MEN1GAAHPGDKMT2A | |
| SCHEMBL9627995 | 0.74 | S100A4 (0.44) | PTPN1HSP90AA1MEN1HTTKMT2A | |
| SCHEMBL9713840 | 0.71 | S100A4 (0.44) | PTPN1HSP90AA1MEN1GAAHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5091558-A | Topical administeration | SYNTEX (U.S.A.) INC. (US) | 1992-02-25 | — | — | US | disclosed |