Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | S100A4 | P26447 | 3/20 | 0.44 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.39 |
| ▸ | PTPN1 | P18031 | 2/20 | 0.39 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.37 |
| ▸ | PPOX | P50336 | 1/20 | 0.37 |
| ▸ | SOAT1 | P35610 | 2/20 | 0.35 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.35 |
| ▸ | USP8 | P40818 | 1/20 | 0.35 |
| ▸ | USP7 | Q93009 | 1/20 | 0.35 |
| ▸ | CES1 | P23141 | 2/20 | 0.34 |
| ▸ | TGM2 | P21980 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 2/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.34 |
| ▸ | NSD2 | O96028 | 1/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 2/20 | 0.33 |
| ▸ | PKM | P14618 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23271842 | 0.87 | S100A4 (0.47) | S100A4HSP90AA1PTPN1SIGMAR1PPOX | |
| SCHEMBL9236755 | 0.82 | SIGMAR1 (0.52) | S100A4HSP90AA1SIGMAR1PPOXCES1 | |
| SCHEMBL9628697 | 0.82 | MAOA (0.47) | PTPN1SOAT1USP8USP7MEN1 | |
| SCHEMBL9628260 | 0.81 | PARK7 (0.40) | S100A4PTPN1SIGMAR1SOAT1USP8 | |
| SCHEMBL9713666 | 0.78 | PTPN1 (0.37) | S100A4PTPN1SOAT1MEN1KMT2A | |
| SCHEMBL1137898 | 0.78 | PTPN1 (0.56) | S100A4PTPN1SOAT1MEN1KMT2A | |
| SCHEMBL9627970 | 0.74 | ALDH1A1 (0.57) | S100A4HSP90AA1PTPN1PPOXPTPN11 | |
| SCHEMBL23271777 | 0.74 | S100A4 (0.52) | S100A4HSP90AA1PTPN1PPOXPTPN11 | |
| SCHEMBL9713511 | 0.74 | S100A4 (0.41) | S100A4HSP90AA1PTPN1PPOXCES1 | |
| SCHEMBL9713423 | 0.74 | PTPN1 (0.46) | S100A4HSP90AA1PTPN1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5155132-A | Nonsteroidal antiinflammatory agents; treating psoriasis | SYNTEX (U.S.A.) INC. (US) | 1992-10-13 | — | — | US | disclosed |
| US-5134161-A | Enzyme inhibitors for skin disorders, antiinflammatory agents | SYNTEX (U.S.A.) INC. (US) | 1992-07-28 | — | — | US | disclosed |
| US-5091558-A | Topical administeration | SYNTEX (U.S.A.) INC. (US) | 1992-02-25 | — | — | US | disclosed |
| US-5089657-A | Topical antiinflammatory agents | SYNTEX (U.S.A.) INC. (US) | 1992-02-18 | — | — | US | disclosed |
| US-4786652-A | TOPICAL ADMINISTRATION | SYNTEX (U.S.A.) INC. (US) | 1988-11-22 | — | — | US | disclosed |
| EP-0282056-A2 | Naphthalene anti-psoriatic agents | SYNTEX (U.S.A.) INC. (US) | 1988-09-14 | — | — | EP | disclosed |
| EP-0282006-A1 | Naphtalene anti-psoriatic agents | SYNTEX (U.S.A.) INC. (US) | 1988-09-14 | — | — | EP | disclosed |
| EP-0150831-B1 | NAPHTHALENE ANTI-PSORIATIC AGENTS | SYNTEX (U.S.A.) INC. (US) | 1988-08-10 | — | — | EP | disclosed |
| US-4758587-A | Naphthalene anti-psoriatic agents | SYNTEX (U.S.A.) INC. (US) | 1988-07-19 | — | — | US | disclosed |
| EP-0150831-A2 | Naphthalene anti-psoriatic agents | SYNTEX (U.S.A.) INC. (US) | 1985-08-07 | — | — | EP | disclosed |