Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | S100A4 | P26447 | 2/20 | 0.44 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.42 |
| ▸ | PPOX | P50336 | 1/20 | 0.40 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | PLIN1 | O60240 | 1/20 | 0.36 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.36 |
| ▸ | USP2 | O75604 | 1/20 | 0.36 |
| ▸ | GSR | P00390 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | TP53 | P04637 | 1/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | HSPD1 | P10809 | 1/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9627970 | 0.81 | ALDH1A1 (0.57) | S100A4HSP90AA1PPOXPTPN11ALDH1A1 | |
| SCHEMBL9713148 | 0.78 | S100A4 (0.40) | S100A4HSP90AA1PPOXPTPN11ALDH1A1 | |
| SCHEMBL357221 | 0.75 | ALDH1A1 (0.63) | S100A4ALDH1A1MEN1PLIN1NR1I2 | |
| SCHEMBL9713740 | 0.73 | BACE1 (0.45) | S100A4HSP90AA1PTPN11MEN1CYP1A2 | |
| SCHEMBL10502720 | 0.73 | S100A4 (0.55) | S100A4HSP90AA1PPOXALDH1A1IDO1 | |
| SCHEMBL9713423 | 0.71 | PTPN1 (0.46) | S100A4HSP90AA1MEN1GAAHPGD | |
| SCHEMBL8773066 | 0.69 | S100A4 (0.56) | S100A4HSP90AA1PPOXPTPN11PTPN1 | |
| SCHEMBL15821387 | 0.69 | S100A4 (0.50) | S100A4HSP90AA1PPOXPTPN11PTPN1 | |
| SCHEMBL8773134 | 0.68 | S100A4 (0.58) | S100A4HSP90AA1PPOXPTPN11IDO1 | |
| SCHEMBL23271777 | 0.67 | S100A4 (0.52) | S100A4HSP90AA1PPOXPTPN11ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5091558-A | Topical administeration | SYNTEX (U.S.A.) INC. (US) | 1992-02-25 | — | — | US | disclosed |
| EP-0150831-B1 | NAPHTHALENE ANTI-PSORIATIC AGENTS | SYNTEX (U.S.A.) INC. (US) | 1988-08-10 | — | — | EP | disclosed |
| EP-0150831-A2 | Naphthalene anti-psoriatic agents | SYNTEX (U.S.A.) INC. (US) | 1985-08-07 | — | — | EP | disclosed |