Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAPDH | P04406 | 1/20 | 0.46 |
| ▸ | CDC25B | P30305 | 2/20 | 0.43 |
| ▸ | PTPRC | P08575 | 1/20 | 0.43 |
| ▸ | P4HB | P07237 | 4/20 | 0.41 |
| ▸ | CES2 | O00748 | 1/20 | 0.40 |
| ▸ | CES1 | P23141 | 1/20 | 0.40 |
| ▸ | IDO1 | P14902 | 1/20 | 0.39 |
| ▸ | CDC25A | P30304 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | NSD2 | O96028 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | MAOA | P21397 | 1/20 | 0.38 |
| ▸ | MAOB | P27338 | 1/20 | 0.38 |
| ▸ | BCL2 | P10415 | 4/20 | 0.37 |
| ▸ | MCL1 | Q07820 | 4/20 | 0.37 |
| ▸ | PTGIR | P43119 | 3/20 | 0.36 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.35 |
| ▸ | G6PD | P11413 | 1/20 | 0.34 |
| ▸ | CCR6 | P51684 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11252090 | 0.85 | CDC25B (0.50) | GAPDHCDC25BPTPRCCES2CES1 | |
| SCHEMBL9643147 | 0.82 | BCL2 (0.44) | PTPRCP4HBMEN1NSD2KMT2A | |
| SCHEMBL11252510 | 0.80 | GAPDH (0.50) | GAPDHCDC25BPTPRCCES2CES1 | |
| SCHEMBL9713600 | 0.80 | CDC25B (0.53) | GAPDHCDC25BPTPRCIDO1CDC25A | |
| SCHEMBL9713721 | 0.79 | P4HB (0.44) | GAPDHP4HBCES2CES1IDO1 | |
| SCHEMBL9628193 | 0.77 | CDC25B (0.54) | GAPDHCDC25BPTPRCCES2CES1 | |
| SCHEMBL9713780 | 0.76 | IDO1 (0.50) | GAPDHCDC25BP4HBCES2CES1 | |
| SCHEMBL9713431 | 0.76 | BCL2 (0.54) | GAPDHCDC25BCES2CES1IDO1 | |
| SCHEMBL9627491 | 0.74 | CDC25B (0.53) | GAPDHCDC25BPTPRCCES2CES1 | |
| SCHEMBL9713793 | 0.73 | CDC25B (0.53) | GAPDHCDC25BPTPRCIDO1CDC25A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5091558-A | Topical administeration | SYNTEX (U.S.A.) INC. (US) | 1992-02-25 | — | — | US | disclosed |
| EP-0150831-B1 | NAPHTHALENE ANTI-PSORIATIC AGENTS | SYNTEX (U.S.A.) INC. (US) | 1988-08-10 | — | — | EP | disclosed |
| EP-0150831-A2 | Naphthalene anti-psoriatic agents | SYNTEX (U.S.A.) INC. (US) | 1985-08-07 | — | — | EP | disclosed |