Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BCL2 | P10415 | 4/20 | 0.45 |
| ▸ | MCL1 | Q07820 | 4/20 | 0.45 |
| ▸ | HKDC1 | Q2TB90 | 2/20 | 0.42 |
| ▸ | MAPT | P10636 | 2/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
| ▸ | CDC25A | P30304 | 5/20 | 0.39 |
| ▸ | CDC25B | P30305 | 5/20 | 0.39 |
| ▸ | PTPN1 | P18031 | 3/20 | 0.39 |
| ▸ | MAP2K7 | O14733 | 2/20 | 0.38 |
| ▸ | MAOA | P21397 | 1/20 | 0.38 |
| ▸ | MAOB | P27338 | 1/20 | 0.38 |
| ▸ | S100A4 | P26447 | 3/20 | 0.36 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17242653 | 0.78 | HKDC1 (0.49) | HKDC1MAPTL3MBTL1MEN1KMT2A | |
| SCHEMBL9713458 | 0.77 | HSD17B10 (0.36) | BCL2MCL1HKDC1MAPTL3MBTL1 | |
| SCHEMBL11294862 | 0.72 | ELANE (0.55) | BCL2MCL1HKDC1MAPTL3MBTL1 | |
| SCHEMBL9239364 | 0.71 | BCL2 (0.47) | BCL2MCL1MAPTL3MBTL1MEN1 | |
| SCHEMBL9811057 | 0.70 | ELANE (0.53) | BCL2MCL1MAPTL3MBTL1MEN1 | |
| SCHEMBL1038715 | 0.67 | BCL2 (0.80) | BCL2MCL1HKDC1MAPTL3MBTL1 | |
| SCHEMBL17250420 | 0.67 | MAPK1 (0.50) | HKDC1MAPTL3MBTL1MEN1KMT2A | |
| SCHEMBL9713666 | 0.67 | PTPN1 (0.37) | L3MBTL1MEN1KMT2APTPN1S100A4 | |
| SCHEMBL9738860 | 0.67 | BCL2 (0.73) | BCL2MCL1HKDC1MAPTL3MBTL1 | |
| SCHEMBL10502055 | 0.66 | MAPT (0.70) | BCL2MCL1HKDC1MAPTL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5091558-A | Topical administeration | SYNTEX (U.S.A.) INC. (US) | 1992-02-25 | — | — | US | disclosed |
| EP-0150831-B1 | NAPHTHALENE ANTI-PSORIATIC AGENTS | SYNTEX (U.S.A.) INC. (US) | 1988-08-10 | — | — | EP | disclosed |
| EP-0150831-A2 | Naphthalene anti-psoriatic agents | SYNTEX (U.S.A.) INC. (US) | 1985-08-07 | — | — | EP | disclosed |