Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 2/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | LMNA | P02545 | 2/20 | 0.36 |
| ▸ | MAPT | P10636 | 2/20 | 0.36 |
| ▸ | MITF | O75030 | 1/20 | 0.36 |
| ▸ | USP2 | O75604 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | BCL2 | P10415 | 4/20 | 0.35 |
| ▸ | MCL1 | Q07820 | 4/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | HTR7 | P34969 | 1/20 | 0.32 |
| ▸ | NPC1 | O15118 | 1/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.32 |
| ▸ | RAB9A | P51151 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.32 |
| ▸ | IDO1 | P14902 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9627527 | 0.81 | S100A4 (0.50) | KMT2AHTTALDH1A1LMNAMAPT | |
| SCHEMBL9627459 | 0.81 | S100A4 (0.50) | KMT2AHTTALDH1A1LMNAMAPT | |
| SCHEMBL9628399 | 0.80 | MAOA (0.50) | KMT2AHTTALDH1A1LMNAMAPT | |
| SCHEMBL9627695 | 0.79 | PARK7 (0.39) | KMT2AHTTALDH1A1LMNAMAPT | |
| SCHEMBL9628338 | 0.77 | MAPT (0.56) | KMT2AHTTALDH1A1LMNAMAPT | |
| SCHEMBL9713787 | 0.77 | BCL2 (0.45) | KMT2AALDH1A1LMNAMAPTTDP1 | |
| SCHEMBL9713666 | 0.72 | PTPN1 (0.37) | HSD17B10KMT2AHTR7L3MBTL1NSD2 | |
| SCHEMBL29036115 | 0.71 | MCL1 (0.46) | HSD17B10ALDH1A1MAPTBCL2MCL1 | |
| SCHEMBL9685867 | 0.70 | S100A4 (0.57) | TDP1BCL2MCL1MAPK1L3MBTL1 | |
| SCHEMBL11294862 | 0.70 | ELANE (0.55) | KMT2AHTTALDH1A1LMNAMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5091558-A | Topical administeration | SYNTEX (U.S.A.) INC. (US) | 1992-02-25 | — | — | US | disclosed |
| EP-0150831-B1 | NAPHTHALENE ANTI-PSORIATIC AGENTS | SYNTEX (U.S.A.) INC. (US) | 1988-08-10 | — | — | EP | disclosed |
| EP-0150831-A2 | Naphthalene anti-psoriatic agents | SYNTEX (U.S.A.) INC. (US) | 1985-08-07 | — | — | EP | disclosed |