Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTPN1 | P18031 | 1/20 | 0.37 |
| ▸ | SOAT1 | P35610 | 13/20 | 0.36 |
| ▸ | S100A4 | P26447 | 3/20 | 0.36 |
| ▸ | HTR7 | P34969 | 1/20 | 0.35 |
| ▸ | PKM | P14618 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | NSD2 | O96028 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9628697 | 0.80 | MAOA (0.47) | PTPN1SOAT1PKMKMT2AMEN1 | |
| SCHEMBL9627995 | 0.78 | S100A4 (0.44) | PTPN1SOAT1S100A4PKMKMT2A | |
| SCHEMBL9628260 | 0.78 | PARK7 (0.40) | PTPN1SOAT1S100A4PKMKMT2A | |
| SCHEMBL1137898 | 0.75 | PTPN1 (0.56) | PTPN1SOAT1S100A4PKMKMT2A | |
| SCHEMBL9713488 | 0.72 | IDO1 (0.57) | PTPN1SOAT1S100A4KMT2AMEN1 | |
| SCHEMBL9713458 | 0.72 | HSD17B10 (0.36) | S100A4HTR7KMT2ANSD2L3MBTL1 | |
| SCHEMBL9627921 | 0.69 | PPARG (0.57) | PTPN1SOAT1 | |
| SCHEMBL29036115 | 0.68 | MCL1 (0.46) | S100A4HSD17B10 | |
| SCHEMBL11294862 | 0.68 | ELANE (0.55) | SOAT1S100A4KMT2AMEN1NSD2 | |
| SCHEMBL9713787 | 0.67 | BCL2 (0.45) | PTPN1S100A4KMT2AMEN1L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5091558-A | Topical administeration | SYNTEX (U.S.A.) INC. (US) | 1992-02-25 | — | — | US | disclosed |
| EP-0150831-B1 | NAPHTHALENE ANTI-PSORIATIC AGENTS | SYNTEX (U.S.A.) INC. (US) | 1988-08-10 | — | — | EP | disclosed |
| EP-0150831-A2 | Naphthalene anti-psoriatic agents | SYNTEX (U.S.A.) INC. (US) | 1985-08-07 | — | — | EP | disclosed |