Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.34 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.34 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.33 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.33 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.32 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.32 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.32 |
| ▸ | MEN1 | O00255 | 2/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | ATM | Q13315 | 2/20 | 0.32 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.32 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.31 |
| ▸ | POLB | P06746 | 1/20 | 0.31 |
| ▸ | APEX1 | P27695 | 1/20 | 0.31 |
| ▸ | ELANE | P08246 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11037114 | 0.91 | GAA (0.36) | GAAALDH1A1ALOX15ABCB11GABRA1 | |
| SCHEMBL9643543 | 0.86 | ABCB11 (0.41) | GAAAKR1B1ALDH1A1TAS1R3TAS1R1 | |
| SCHEMBL9642598 | 0.80 | GAA (0.37) | GAAALDH1A1TAS1R3TAS1R1ALOX15 | |
| SCHEMBL9641729 | 0.79 | ABCB11 (0.37) | GAAAKR1B1TAS1R3TAS1R1ALOX15 | |
| SCHEMBL9641747 | 0.78 | AKR1B1 (0.45) | GAAAKR1B1ALDH1A1ALOX15KDM4E | |
| SCHEMBL9713474 | 0.77 | KMT2A (0.42) | GAAALDH1A1KMT2AMEN1CYP2C19 | |
| SCHEMBL9642806 | 0.72 | AKR1B1 (0.39) | GAAAKR1B1ALDH1A1TAS1R3TAS1R1 | |
| SCHEMBL20398634 | 0.72 | GAA (0.45) | GAAALDH1A1ALOX15KMT2AMEN1 | |
| SCHEMBL9642066 | 0.72 | ABCB11 (0.48) | ALDH1A1ALOX15ABCB11KMT2AKDM4E | |
| SCHEMBL9643555 | 0.70 | ALDH1A1 (0.44) | GAAAKR1B1ALDH1A1ALOX15ABCB11 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5091558-A | Topical administeration | SYNTEX (U.S.A.) INC. (US) | 1992-02-25 | — | — | US | disclosed |
| EP-0150831-B1 | NAPHTHALENE ANTI-PSORIATIC AGENTS | SYNTEX (U.S.A.) INC. (US) | 1988-08-10 | — | — | EP | disclosed |