Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 5/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.42 |
| ▸ | NOD2 | Q9HC29 | 1/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | PKM | P14618 | 1/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
| ▸ | AKR1C3 | P42330 | 2/20 | 0.37 |
| ▸ | AKR1C2 | P52895 | 2/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9713795 | 0.77 | GAA (0.39) | KMT2AALDH1A1CYP2C19GAANPSR1 | |
| SCHEMBL9713598 | 0.73 | GAA (0.40) | KMT2AALDH1A1NOD2TDP1NPC1 | |
| SCHEMBL16604884 | 0.68 | ESR1 (0.44) | KMT2AALDH1A1NOD2TDP1CYP1A2 | |
| SCHEMBL11037114 | 0.68 | GAA (0.36) | KMT2AALDH1A1GAANPSR1MEN1 | |
| SCHEMBL31321661 | 0.68 | MAPT (0.56) | KMT2AALDH1A1TDP1HPGDL3MBTL1 | |
| SCHEMBL9629261 | 0.68 | ABCB11 (0.54) | ALDH1A1NPC1HPGDRAB9ASMN1; SMN2 | |
| SCHEMBL9643555 | 0.67 | ALDH1A1 (0.44) | KMT2AALDH1A1HPGDSMN1; SMN2GAA | |
| SCHEMBL29371748 | 0.67 | KMT2A (0.53) | KMT2AALDH1A1NOD2TDP1CYP1A2 | |
| SCHEMBL9629394 | 0.67 | KDM4E (0.56) | KMT2AALDH1A1CYP1A2CYP2C9NPC1 | |
| SCHEMBL23152131 | 0.67 | ALDH1A1 (0.60) | KMT2AALDH1A1NOD2TDP1CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5091558-A | Topical administeration | SYNTEX (U.S.A.) INC. (US) | 1992-02-25 | — | — | US | disclosed |
| EP-0150831-B1 | NAPHTHALENE ANTI-PSORIATIC AGENTS | SYNTEX (U.S.A.) INC. (US) | 1988-08-10 | — | — | EP | disclosed |
| EP-0150831-A2 | Naphthalene anti-psoriatic agents | SYNTEX (U.S.A.) INC. (US) | 1985-08-07 | — | — | EP | disclosed |