Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AKR1B1 | P15121 | 3/20 | 0.45 |
| ▸ | ELANE | P08246 | 1/20 | 0.42 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.41 |
| ▸ | LDHA | P00338 | 1/20 | 0.41 |
| ▸ | LDHB | P07195 | 1/20 | 0.41 |
| ▸ | FPR1 | P21462 | 1/20 | 0.39 |
| ▸ | TOP2A | P11388 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
| ▸ | LMNA | P02545 | 3/20 | 0.37 |
| ▸ | PAM | P19021 | 2/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | TRPV1 | Q8NER1 | 3/20 | 0.36 |
| ▸ | DGKA | P23743 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9643146 | 0.84 | ABCB11 (0.52) | ELANEALOX15TOP2AMAPTTRPV1 | |
| SCHEMBL9641664 | 0.84 | ABCB11 (0.52) | ELANEALOX15TOP2AMAPTTRPV1 | |
| SCHEMBL9643543 | 0.84 | ABCB11 (0.41) | AKR1B1ELANEALOX15LDHALDHB | |
| SCHEMBL9641940 | 0.82 | AKR1B1 (0.41) | AKR1B1ALOX15LDHALDHBMAPT | |
| SCHEMBL9642125 | 0.81 | THRA (0.43) | AKR1B1LDHALDHB | |
| SCHEMBL9642598 | 0.80 | GAA (0.37) | ALOX15GAAKDM4EALDH1A1SMN1; SMN2 | |
| SCHEMBL9713795 | 0.78 | GAA (0.39) | AKR1B1ELANEALOX15GAAKDM4E | |
| SCHEMBL9641729 | 0.77 | ABCB11 (0.37) | AKR1B1ELANEALOX15LDHALDHB | |
| SCHEMBL9642627 | 0.77 | ALOX15 (0.43) | AKR1B1ALOX15TOP2AMAPTLMNA | |
| SCHEMBL9641652 | 0.76 | AKR1B1 (0.43) | AKR1B1ALOX15LDHALDHBLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0215622-B1 | NAPHTHALENE ANTI-PSORIATIC AGENTS AND PROCESS FOR MAKING THEM | SYNTEX (U.S.A.) INC. (US) | 1992-06-17 | — | — | EP | disclosed |
| US-4946845-A | STABLE ANTIINFLAMMATORY AGENTS, LIPOXYGENASE INHIBITORS | SYNTEX (U.S.A.) INC. (US) | 1990-08-07 | — | — | US | disclosed |
| US-4792556-A | LIPOXYGENASE INHIBITORS | SYNTEX (U.S.A.) INC. (US) | 1988-12-20 | — | — | US | disclosed |
| EP-0215622-A2 | Naphthalene anti-psoriatic agents and process for making them | SYNTEX (U.S.A.) INC. (US) | 1987-03-25 | — | — | EP | disclosed |