Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.56 |
| ▸ | RECQL | P46063 | 1/20 | 0.56 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.50 |
| ▸ | CA1 | P00915 | 3/20 | 0.47 |
| ▸ | CA2 | P00918 | 3/20 | 0.47 |
| ▸ | CA12 | O43570 | 1/20 | 0.47 |
| ▸ | CA3 | P07451 | 1/20 | 0.47 |
| ▸ | CA4 | P22748 | 1/20 | 0.47 |
| ▸ | CA6 | P23280 | 1/20 | 0.47 |
| ▸ | CA5A | P35218 | 1/20 | 0.47 |
| ▸ | CA7 | P43166 | 1/20 | 0.47 |
| ▸ | CA9 | Q16790 | 1/20 | 0.47 |
| ▸ | CA13 | Q8N1Q1 | 1/20 | 0.47 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.47 |
| ▸ | CA5B | Q9Y2D0 | 1/20 | 0.47 |
| ▸ | POLB | P06746 | 3/20 | 0.47 |
| ▸ | CYTH2 | Q99418 | 1/20 | 0.45 |
| ▸ | ABCC9 | O60706 | 1/20 | 0.43 |
| ▸ | ABCC8 | Q09428 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9713970 | 0.85 | MAPT (0.59) | ALDH1A1RECQLHSD17B10KMT2ACA1 | |
| SCHEMBL9713847 | 0.85 | KMT2A (0.50) | ALDH1A1RECQLHSD17B10KMT2ACA1 | |
| SCHEMBL9713773 | 0.83 | KMT2A (0.56) | ALDH1A1KMT2ACA1CA2CA12 | |
| SCHEMBL9713843 | 0.83 | MAPT (0.50) | ALDH1A1KMT2APOLBCYTH2ABCC9 | |
| SCHEMBL4471540 | 0.81 | ALDH1A1 (0.78) | ALDH1A1RECQLHSD17B10KMT2ACA1 | |
| SCHEMBL9713771 | 0.81 | MAPT (0.60) | ALDH1A1KMT2APOLBMEN1EPHX2 | |
| SCHEMBL9713975 | 0.81 | HTR6 (0.50) | ALDH1A1KMT2ACA1CA2CA12 | |
| SCHEMBL9713607 | 0.80 | MAPT (0.59) | ALDH1A1KMT2APOLBMEN1EPHX2 | |
| SCHEMBL9713834 | 0.79 | L3MBTL1 (0.51) | ALDH1A1RECQLKMT2ACA1CA2 | |
| SCHEMBL9713819 | 0.79 | MAPT (0.49) | ALDH1A1KMT2AMEN1RAB9AMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5084449-A | Bactericides and antiprotozoa agents | DR. KARL THOMAE GMBH (DE) | 1992-01-28 | — | — | US | disclosed |
| US-4992430-A | Anti-bacterial compositions comprising a substituted bis-(4-aminophenyl)-sulfone and a dihydro-folic acid reductase | DR. KARL THOMAE GMBH (DE) | 1991-02-12 | — | — | US | disclosed |
| US-4829058-A | INHIBITORS OF BACTERIA, MYCOBACTERIA AND PLASMODIA | DR. KARL THOMAE GMBH (DE) | 1989-05-09 | — | — | US | disclosed |
| EP-0165422-A1 | Substituted bis-(4-aminophenyl)-sulphones, their preparation and their use as medicines | Dr. Karl Thomae GmbH (DE) | 1985-12-27 | — | — | EP | disclosed |