Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX5 | P09917 | 17/20 | 0.48 |
| ▸ | ELANE | P08246 | 1/20 | 0.47 |
| ▸ | MAOA | P21397 | 1/20 | 0.45 |
| ▸ | MAOB | P27338 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | THRB | P10828 | 1/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
| ▸ | MPEG1 | Q2M385 | 3/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9627585 | 0.94 | ALDH1A1 (0.51) | ALOX5ELANEALDH1A1MAPTTHRB | |
| SCHEMBL9627210 | 0.91 | ELANE (0.50) | ALOX5ELANEMAOAMAOBALDH1A1 | |
| SCHEMBL9713844 | 0.87 | ELANE (0.46) | ALOX5ELANEMAOAMAOBALDH1A1 | |
| SCHEMBL21469361 | 0.82 | MAOA (0.59) | ELANEMAOAMAOBALDH1A1MAPT | |
| SCHEMBL9628157 | 0.80 | ALOX5 (0.55) | ALOX5ALDH1A1MAPTTHRBTDP1 | |
| SCHEMBL9713639 | 0.79 | MAOA (0.47) | ALOX5ELANEMAOAMAOBALDH1A1 | |
| SCHEMBL9642524 | 0.79 | ELANE (0.67) | ELANEMAOAMAOBALDH1A1MAPT | |
| SCHEMBL11660838 | 0.79 | ALOX5 (0.57) | ALOX5ALDH1A1MAPTTHRBTDP1 | |
| SCHEMBL10951203 | 0.79 | ALOX5 (0.57) | ALOX5ALDH1A1MAPTTHRBTDP1 | |
| SCHEMBL9628375 | 0.79 | ALOX5 (0.57) | ALOX5ALDH1A1MAPTTHRBTDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5091558-A | Topical administeration | SYNTEX (U.S.A.) INC. (US) | 1992-02-25 | — | — | US | disclosed |
| EP-0150831-B1 | NAPHTHALENE ANTI-PSORIATIC AGENTS | SYNTEX (U.S.A.) INC. (US) | 1988-08-10 | — | — | EP | disclosed |
| EP-0150831-A2 | Naphthalene anti-psoriatic agents | SYNTEX (U.S.A.) INC. (US) | 1985-08-07 | — | — | EP | disclosed |