Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOA | P21397 | 1/20 | 0.47 |
| ▸ | MAOB | P27338 | 1/20 | 0.47 |
| ▸ | ELANE | P08246 | 2/20 | 0.46 |
| ▸ | LCK | P06239 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 3/20 | 0.42 |
| ▸ | TP53 | P04637 | 2/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.42 |
| ▸ | NPC1 | O15118 | 2/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.42 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.42 |
| ▸ | RELA | Q04206 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | ALOX5 | P09917 | 9/20 | 0.41 |
| ▸ | MPEG1 | Q2M385 | 7/20 | 0.41 |
| ▸ | MAPT | P10636 | 4/20 | 0.41 |
| ▸ | XIAP | P98170 | 3/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.41 |
| ▸ | GPR84 | Q9NQS5 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21469361 | 0.84 | MAOA (0.59) | MAOAMAOBELANELCKRAB9A | |
| SCHEMBL8993532 | 0.84 | MAOA (0.53) | MAOAMAOBELANELCKRAB9A | |
| SCHEMBL9713816 | 0.79 | ALOX5 (0.48) | MAOAMAOBELANEALOX5MPEG1 | |
| SCHEMBL571621 | 0.79 | MAOA (0.56) | MAOAMAOBELANELCKTP53 | |
| SCHEMBL572120 | 0.79 | MAOA (0.56) | MAOAMAOBELANELCKTP53 | |
| SCHEMBL9713844 | 0.78 | ELANE (0.46) | MAOAMAOBELANERAB9ATP53 | |
| SCHEMBL9353826 | 0.78 | MAOA (0.68) | MAOAMAOBELANELCKPOLB | |
| SCHEMBL9627893 | 0.77 | MAOA (0.45) | MAOAMAOBELANELCKTP53 | |
| SCHEMBL3273093 | 0.76 | ALOX5 (0.55) | RAB9ATP53MAPK1ALOX5MPEG1 | |
| SCHEMBL9857129 | 0.76 | ALOX5 (0.55) | RAB9ATP53MAPK1ALOX5MPEG1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5091558-A | Topical administeration | SYNTEX (U.S.A.) INC. (US) | 1992-02-25 | — | — | US | disclosed |
| EP-0150831-B1 | NAPHTHALENE ANTI-PSORIATIC AGENTS | SYNTEX (U.S.A.) INC. (US) | 1988-08-10 | — | — | EP | disclosed |
| EP-0150831-A2 | Naphthalene anti-psoriatic agents | SYNTEX (U.S.A.) INC. (US) | 1985-08-07 | — | — | EP | disclosed |