Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 6/20 | 0.46 |
| ▸ | POLB | P06746 | 3/20 | 0.46 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 5/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.40 |
| ▸ | PNLIP | P16233 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 5/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.39 |
| ▸ | GAA | P10253 | 3/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
| ▸ | JAK2 | O60674 | 1/20 | 0.38 |
| ▸ | USP2 | O75604 | 1/20 | 0.38 |
| ▸ | ESR1 | P03372 | 1/20 | 0.38 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9627668 | 0.87 | KMT2A (0.50) | POLBLMNASMN1; SMN2MAPTKMT2A | |
| SCHEMBL9643247 | 0.84 | ABCB11 (0.47) | L3MBTL1POLBMRGPRX4MAPK1LMNA | |
| SCHEMBL9713245 | 0.84 | ABCB11 (0.53) | L3MBTL1POLBMRGPRX4LMNASMN1; SMN2 | |
| SCHEMBL10502679 | 0.81 | ABCB11 (0.46) | L3MBTL1POLBLMNASMN1; SMN2CYP2C9 | |
| SCHEMBL29372079 | 0.80 | ABCB11 (0.49) | POLBLMNASMN1; SMN2MAPTKMT2A | |
| SCHEMBL9713437 | 0.78 | PDE7A (0.40) | L3MBTL1POLBMAPK1LMNASMN1; SMN2 | |
| SCHEMBL9656747 | 0.78 | KMT2A (0.42) | L3MBTL1POLBMAPK1CYP1A2CYP3A4 | |
| SCHEMBL9658254 | 0.77 | ALDH1A1 (0.48) | L3MBTL1CYP1A2CYP2C9CYP2C19GAA | |
| SCHEMBL9713650 | 0.76 | SMN1; SMN2 (0.41) | L3MBTL1LMNASMN1; SMN2MAPTKMT2A | |
| SCHEMBL9643206 | 0.76 | ABCB11 (0.44) | POLBMRGPRX4LMNASMN1; SMN2PNLIP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5091558-A | Topical administeration | SYNTEX (U.S.A.) INC. (US) | 1992-02-25 | — | — | US | disclosed |
| EP-0150831-B1 | NAPHTHALENE ANTI-PSORIATIC AGENTS | SYNTEX (U.S.A.) INC. (US) | 1988-08-10 | — | — | EP | disclosed |
| EP-0150831-A2 | Naphthalene anti-psoriatic agents | SYNTEX (U.S.A.) INC. (US) | 1985-08-07 | — | — | EP | disclosed |