Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.41 |
| ▸ | PPARA | Q07869 | 8/20 | 0.41 |
| ▸ | PPARG | P37231 | 7/20 | 0.41 |
| ▸ | LTA4H | P09960 | 1/20 | 0.40 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | CNR2 | P34972 | 1/20 | 0.39 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | ATM | Q13315 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9641852 | 0.80 | ABCB11 (0.48) | SMN1; SMN2L3MBTL1KMT2AMAPTATM | |
| SCHEMBL9713758 | 0.79 | L3MBTL1 (0.48) | SMN1; SMN2PPARAPPARGL3MBTL1LMNA | |
| SCHEMBL9656747 | 0.79 | KMT2A (0.42) | PPARAPPARGL3MBTL1GAAFFAR1 | |
| SCHEMBL9658254 | 0.78 | ALDH1A1 (0.48) | L3MBTL1GAAATMTAAR1 | |
| SCHEMBL9713245 | 0.77 | ABCB11 (0.53) | SMN1; SMN2L3MBTL1LMNAGAAKMT2A | |
| SCHEMBL9713732 | 0.77 | ABCB11 (0.56) | SMN1; SMN2L3MBTL1LMNAGAAFFAR1 | |
| SCHEMBL9643180 | 0.77 | CHRM1 (0.49) | SMN1; SMN2PPARAL3MBTL1LMNAFFAR1 | |
| SCHEMBL9641776 | 0.77 | L3MBTL1 (0.43) | SMN1; SMN2L3MBTL1LMNAMAPTATM | |
| SCHEMBL9713839 | 0.76 | L3MBTL1 (0.46) | SMN1; SMN2L3MBTL1LMNAGAAKMT2A | |
| SCHEMBL9643296 | 0.76 | ALDH1A1 (0.43) | SMN1; SMN2L3MBTL1KMT2AMAPTATM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5091558-A | Topical administeration | SYNTEX (U.S.A.) INC. (US) | 1992-02-25 | — | — | US | disclosed |
| EP-0150831-B1 | NAPHTHALENE ANTI-PSORIATIC AGENTS | SYNTEX (U.S.A.) INC. (US) | 1988-08-10 | — | — | EP | disclosed |
| EP-0150831-A2 | Naphthalene anti-psoriatic agents | SYNTEX (U.S.A.) INC. (US) | 1985-08-07 | — | — | EP | disclosed |