Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CES2 | O00748 | 7/20 | 0.60 |
| ▸ | CES1 | P23141 | 7/20 | 0.60 |
| ▸ | GAPDH | P04406 | 4/20 | 0.56 |
| ▸ | MAOA | P21397 | 1/20 | 0.46 |
| ▸ | MAOB | P27338 | 1/20 | 0.46 |
| ▸ | ELANE | P08246 | 1/20 | 0.44 |
| ▸ | S100A4 | P26447 | 1/20 | 0.44 |
| ▸ | P4HB | P07237 | 1/20 | 0.43 |
| ▸ | ALKBH3 | Q96Q83 | 1/20 | 0.41 |
| ▸ | IDO1 | P14902 | 1/20 | 0.41 |
| ▸ | CDC25A | P30304 | 1/20 | 0.41 |
| ▸ | CDC25B | P30305 | 1/20 | 0.41 |
| ▸ | LCK | P06239 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9849815 | 0.85 | CES2 (0.77) | CES2CES1GAPDHMAOAMAOB | |
| SCHEMBL9627801 | 0.81 | CDC25A (0.62) | CES2CES1GAPDHMAOAMAOB | |
| SCHEMBL9713675 | 0.77 | CES2 (0.60) | CES2CES1GAPDHMAOAMAOB | |
| SCHEMBL9627491 | 0.77 | CDC25B (0.53) | CES2CES1GAPDHMAOAMAOB | |
| SCHEMBL17594909 | 0.75 | GAPDH (0.89) | CES2CES1GAPDHMAOAMAOB | |
| SCHEMBL9654781 | 0.75 | GAPDH (0.69) | CES2CES1GAPDHMAOAMAOB | |
| SCHEMBL9628489 | 0.75 | CDC25A (0.62) | GAPDHMAOAMAOBELANES100A4 | |
| SCHEMBL5820386 | 0.73 | ALDH1A1 (0.61) | MAOAMAOBELANEALKBH3IDO1 | |
| SCHEMBL9628251 | 0.72 | CES1 (0.77) | CES2CES1GAPDHP4HBIDO1 | |
| SCHEMBL29647693 | 0.72 | CES1 (0.77) | CES2CES1GAPDHP4HBIDO1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5091558-A | Topical administeration | SYNTEX (U.S.A.) INC. (US) | 1992-02-25 | — | — | US | disclosed |
| EP-0150831-B1 | NAPHTHALENE ANTI-PSORIATIC AGENTS | SYNTEX (U.S.A.) INC. (US) | 1988-08-10 | — | — | EP | disclosed |
| EP-0150831-A2 | Naphthalene anti-psoriatic agents | SYNTEX (U.S.A.) INC. (US) | 1985-08-07 | — | — | EP | disclosed |