Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CDC25A | P30304 | 2/20 | 0.41 |
| ▸ | CDC25B | P30305 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.41 |
| ▸ | MAPT | P10636 | 8/20 | 0.41 |
| ▸ | LMNA | P02545 | 5/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 5/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.41 |
| ▸ | HPGD | P15428 | 4/20 | 0.41 |
| ▸ | RAB9A | P51151 | 3/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.41 |
| ▸ | POLB | P06746 | 2/20 | 0.41 |
| ▸ | MAP2K7 | O14733 | 1/20 | 0.41 |
| ▸ | GMNN | O75496 | 1/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.41 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5807365 | 0.82 | ALDH1A1 (0.58) | CDC25ACDC25BALDH1A1MAPTLMNA | |
| SCHEMBL9628254 | 0.81 | MAPT (0.65) | CDC25ACDC25BALDH1A1MAPTLMNA | |
| SCHEMBL9629320 | 0.80 | PPARG (0.48) | CDC25ACDC25BALDH1A1MAPTLMNA | |
| SCHEMBL9627431 | 0.78 | CDC25A (0.65) | CDC25ACDC25BALDH1A1MAPTLMNA | |
| SCHEMBL571497 | 0.76 | NQO1 (0.43) | CDC25ACDC25BALDH1A1MAPTLMNA | |
| SCHEMBL9627624 | 0.76 | CDC25A (0.41) | CDC25ACDC25BALDH1A1MAPTLMNA | |
| SCHEMBL9714008 | 0.73 | XIAP (0.46) | ALDH1A1MAPTLMNAKDM4EHPGD | |
| SCHEMBL14407301 | 0.72 | MAPT (0.55) | CDC25ACDC25BALDH1A1MAPTLMNA | |
| SCHEMBL9677785 | 0.72 | CDC25A (0.42) | CDC25ACDC25BALDH1A1MAPTLMNA | |
| SCHEMBL571247 | 0.70 | MALT1 (0.41) | CDC25ACDC25BALDH1A1KDM4ECYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5091558-A | Topical administeration | SYNTEX (U.S.A.) INC. (US) | 1992-02-25 | — | — | US | disclosed |
| EP-0150831-B1 | NAPHTHALENE ANTI-PSORIATIC AGENTS | SYNTEX (U.S.A.) INC. (US) | 1988-08-10 | — | — | EP | disclosed |
| EP-0150831-A2 | Naphthalene anti-psoriatic agents | SYNTEX (U.S.A.) INC. (US) | 1985-08-07 | — | — | EP | disclosed |