Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | XIAP | P98170 | 1/20 | 0.46 |
| ▸ | NQO1 | P15559 | 4/20 | 0.45 |
| ▸ | POR | P16435 | 4/20 | 0.45 |
| ▸ | IDO1 | P14902 | 2/20 | 0.35 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 5/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.33 |
| ▸ | MEN1 | O00255 | 3/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | RECQL | P46063 | 1/20 | 0.33 |
| ▸ | NPC1 | O15118 | 2/20 | 0.33 |
| ▸ | RAB9A | P51151 | 2/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.33 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8993532 | 0.82 | MAOA (0.53) | XIAPNQO1PORMCL1MAPT | |
| SCHEMBL571497 | 0.79 | NQO1 (0.43) | XIAPNQO1PORIDO1MAPT | |
| SCHEMBL8781044 | 0.78 | APAF1 (0.60) | XIAPMCL1MAPTALDH1A1KDM4E | |
| SCHEMBL9713797 | 0.77 | S100A4 (0.50) | XIAPIDO1MCL1MAPTALDH1A1 | |
| SCHEMBL23271977 | 0.74 | DUSP3 (0.46) | NQO1PORMCL1MAPTALDH1A1 | |
| SCHEMBL30002598 | 0.74 | DUSP3 (0.46) | NQO1PORMCL1MAPTALDH1A1 | |
| SCHEMBL9713867 | 0.73 | CDC25A (0.41) | NQO1PORIDO1MAPTALDH1A1 | |
| SCHEMBL3420118 | 0.69 | NQO1 (0.50) | NQO1PORMCL1MAPTALDH1A1 | |
| SCHEMBL571381 | 0.68 | NQO1 (0.38) | NQO1PORIDO1MAPTALDH1A1 | |
| SCHEMBL10421261 | 0.67 | NQO1 (0.48) | NQO1PORMCL1MAPTALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5091558-A | Topical administeration | SYNTEX (U.S.A.) INC. (US) | 1992-02-25 | — | — | US | disclosed |
| EP-0150831-B1 | NAPHTHALENE ANTI-PSORIATIC AGENTS | SYNTEX (U.S.A.) INC. (US) | 1988-08-10 | — | — | EP | disclosed |
| EP-0150831-A2 | Naphthalene anti-psoriatic agents | SYNTEX (U.S.A.) INC. (US) | 1985-08-07 | — | — | EP | disclosed |