Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM5A | P29375 | 2/20 | 0.49 |
| ▸ | KDM5B | Q9UGL1 | 2/20 | 0.49 |
| ▸ | KDM4A | O75164 | 1/20 | 0.49 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.49 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.44 |
| ▸ | LMNA | P02545 | 3/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | NOD2 | Q9HC29 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.40 |
| ▸ | TP53 | P04637 | 2/20 | 0.40 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 3/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | SLC1A2 | P43004 | 1/20 | 0.39 |
| ▸ | VNN1 | O95497 | 1/20 | 0.39 |
| ▸ | BRD4 | O60885 | 1/20 | 0.39 |
| ▸ | ATM | Q13315 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9714241 | 0.86 | RIPK1 (0.43) | KDM5AKDM5BKDM4AKDM4CLMNA | |
| SCHEMBL9714136 | 0.86 | CYP11B1 (0.43) | KDM5AKDM5BKDM4AKDM4CLMNA | |
| SCHEMBL9714397 | 0.85 | NPC1 (0.45) | KDM4CLMNAHPGDNPC1RAB9A | |
| SCHEMBL10568691 | 0.80 | KDM5A (0.51) | KDM5AKDM5BKDM4AKDM4CL3MBTL1 | |
| SCHEMBL9714605 | 0.79 | CACNA1H (0.39) | KDM5AKDM5BKDM4AKDM4CALDH1A1 | |
| SCHEMBL26276579 | 0.72 | KDM5B (0.50) | KDM5AKDM5BKDM4AKDM4CL3MBTL1 | |
| SCHEMBL9714348 | 0.72 | KDM5B (0.54) | KDM5AKDM5BKDM4AKDM4CL3MBTL1 | |
| SCHEMBL24845157 | 0.72 | KDM5B (0.52) | KDM5AKDM5BKDM4AKDM4CL3MBTL1 | |
| SCHEMBL22747342 | 0.72 | KDM5B (0.47) | KDM5AKDM5BKDM4AKDM4CL3MBTL1 | |
| SCHEMBL9857894 | 0.70 | ALDH1A1 (0.43) | L3MBTL1LMNAHPGDNPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0248414-B1 | ARALKYL IMIDAZOLE DERIVATIVES | CIBA-GEIGY AG (CH) | 1992-09-23 | — | — | EP | disclosed |
| EP-0248414-A2 | Aralkyl imidazole derivatives | CIBA-GEIGY AG (CH) | 1987-12-09 | — | — | EP | disclosed |