Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PKM | P14618 | 3/20 | 0.60 |
| ▸ | IDO1 | P14902 | 2/20 | 0.54 |
| ▸ | POLB | P06746 | 1/20 | 0.54 |
| ▸ | LMNA | P02545 | 1/20 | 0.53 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.53 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.53 |
| ▸ | HTT | P42858 | 1/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.53 |
| ▸ | MEN1 | O00255 | 1/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.53 |
| ▸ | MAPT | P10636 | 1/20 | 0.53 |
| ▸ | GAA | P10253 | 2/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9713788 | 0.84 | PRMT1 (0.57) | LMNAHTTSMN1; SMN2ALDH1A1KDM4E | |
| SCHEMBL9365750 | 0.82 | PKM (0.73) | PKMIDO1LMNAMAPK1SMN1; SMN2 | |
| SCHEMBL28557447 | 0.79 | LMNA (0.64) | PKMIDO1LMNAALOX15MAPK1 | |
| SCHEMBL9713935 | 0.79 | PKM (0.67) | PKMIDO1MAPK1ALDH1A1KDM4E | |
| SCHEMBL13602265 | 0.79 | PKM (0.63) | PKMIDO1LMNAALOX15MAPK1 | |
| SCHEMBL14567709 | 0.78 | LMNA (0.63) | PKMIDO1LMNAALOX15MAPK1 | |
| SCHEMBL23620238 | 0.77 | PKM (1.00) | PKMIDO1POLBLMNASMN1; SMN2 | |
| SCHEMBL13689986 | 0.77 | PKM (0.60) | PKMIDO1LMNAALOX15MAPK1 | |
| SCHEMBL7571133 | 0.76 | MAPT (0.63) | POLBLMNAMAPK1HTTSMN1; SMN2 | |
| SCHEMBL15705234 | 0.76 | IDO1 (0.76) | PKMIDO1LMNAALOX15MAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5084449-A | Bactericides and antiprotozoa agents | DR. KARL THOMAE GMBH (DE) | 1992-01-28 | — | — | US | disclosed |
| US-4992430-A | Anti-bacterial compositions comprising a substituted bis-(4-aminophenyl)-sulfone and a dihydro-folic acid reductase | DR. KARL THOMAE GMBH (DE) | 1991-02-12 | — | — | US | disclosed |
| US-4829058-A | INHIBITORS OF BACTERIA, MYCOBACTERIA AND PLASMODIA | DR. KARL THOMAE GMBH (DE) | 1989-05-09 | — | — | US | disclosed |