Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRMT1 | Q99873 | 1/20 | 0.57 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.51 |
| ▸ | MAPT | P10636 | 4/20 | 0.51 |
| ▸ | HTT | P42858 | 3/20 | 0.51 |
| ▸ | MEN1 | O00255 | 2/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.51 |
| ▸ | USP2 | O75604 | 2/20 | 0.51 |
| ▸ | GAA | P10253 | 1/20 | 0.51 |
| ▸ | CDC7 | O00311 | 1/20 | 0.51 |
| ▸ | EEF2K | O00418 | 1/20 | 0.51 |
| ▸ | PLK4 | O00444 | 1/20 | 0.51 |
| ▸ | AURKA | O14965 | 1/20 | 0.51 |
| ▸ | DYRK3 | O43781 | 1/20 | 0.51 |
| ▸ | RPS6KA5 | O75582 | 1/20 | 0.51 |
| ▸ | PRKD3 | O94806 | 1/20 | 0.51 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.51 |
| ▸ | PIM1 | P11309 | 1/20 | 0.51 |
| ▸ | PHKG2 | P15735 | 1/20 | 0.51 |
| ▸ | CDK2 | P24941 | 1/20 | 0.51 |
| ▸ | AKT1 | P31749 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9714263 | 0.84 | PKM (0.60) | ALDH1A1MAPTHTTMEN1KMT2A | |
| SCHEMBL23093601 | 0.81 | PKM (0.61) | PRMT1ALDH1A1MAPTHTTMEN1 | |
| SCHEMBL1417537 | 0.80 | CA1 (0.71) | PRMT1ALDH1A1MAPTHTTMEN1 | |
| SCHEMBL2240008 | 0.80 | CA1 (0.71) | PRMT1ALDH1A1MAPTHTTMEN1 | |
| SCHEMBL23093373 | 0.79 | PRMT1 (0.62) | PRMT1ALDH1A1MAPTHTTMEN1 | |
| SCHEMBL7571133 | 0.79 | MAPT (0.63) | ALDH1A1MAPTHTTMEN1KMT2A | |
| SCHEMBL23109220 | 0.78 | CDC7 (0.58) | PRMT1ALDH1A1MAPTHTTMEN1 | |
| SCHEMBL11085201 | 0.78 | PRMT1 (0.60) | PRMT1ALDH1A1MAPTHTTMEN1 | |
| SCHEMBL9714094 | 0.77 | HSD11B1 (0.48) | PRMT1ALDH1A1MAPTMEN1KMT2A | |
| SCHEMBL9713763 | 0.77 | HSD11B1 (0.48) | PRMT1ALDH1A1MAPTMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5084449-A | Bactericides and antiprotozoa agents | DR. KARL THOMAE GMBH (DE) | 1992-01-28 | — | — | US | disclosed |
| US-4992430-A | Anti-bacterial compositions comprising a substituted bis-(4-aminophenyl)-sulfone and a dihydro-folic acid reductase | DR. KARL THOMAE GMBH (DE) | 1991-02-12 | — | — | US | disclosed |
| US-4829058-A | INHIBITORS OF BACTERIA, MYCOBACTERIA AND PLASMODIA | DR. KARL THOMAE GMBH (DE) | 1989-05-09 | — | — | US | disclosed |