Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LPAR3 | Q9UBY5 | 3/20 | 0.52 |
| ▸ | LPAR2 | Q9HBW0 | 1/20 | 0.52 |
| ▸ | CETP | P11597 | 1/20 | 0.47 |
| ▸ | GABBR2 | O75899 | 1/20 | 0.47 |
| ▸ | GABRR1 | P24046 | 1/20 | 0.47 |
| ▸ | GABBR1 | Q9UBS5 | 1/20 | 0.47 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.44 |
| ▸ | PPARG | P37231 | 5/20 | 0.43 |
| ▸ | PPARD | Q03181 | 5/20 | 0.43 |
| ▸ | PPARA | Q07869 | 5/20 | 0.43 |
| ▸ | HDAC11 | Q96DB2 | 4/20 | 0.43 |
| ▸ | TSHR | P16473 | 3/20 | 0.43 |
| ▸ | GPR84 | Q9NQS5 | 3/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | TLR2 | O60603 | 2/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.43 |
| ▸ | FABP4 | P15090 | 2/20 | 0.43 |
| ▸ | PTPN1 | P18031 | 2/20 | 0.43 |
| ▸ | SLC22A6 | Q4U2R8 | 1/20 | 0.43 |
| ▸ | SLC22A8 | Q8TCC7 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1315772 | 0.93 | GABBR2 (0.54) | LPAR3LPAR2CETPGABBR2GABRR1 | |
| SCHEMBL1313487 | 0.84 | LMNA (0.48) | LPAR3LPAR2GABBR2GABRR1GABBR1 | |
| SCHEMBL37982 | 0.81 | LPAR3 (0.67) | LPAR3LPAR2CETPGABBR2GABRR1 | |
| SCHEMBL338706 | 0.81 | AKR1B1 (0.54) | LPAR3LPAR2CETPAKR1B1PPARG | |
| SCHEMBL7557652 | 0.80 | LPAR3 (0.45) | LPAR3LPAR2CETPGABBR2GABRR1 | |
| SCHEMBL9290884 | 0.79 | GPR84 (0.56) | LPAR3LPAR2CETPAKR1B1PPARG | |
| SCHEMBL9290873 | 0.79 | GPR84 (0.56) | LPAR3LPAR2CETPAKR1B1PPARG | |
| SCHEMBL339788 | 0.79 | GPR84 (0.56) | LPAR3LPAR2CETPAKR1B1PPARG | |
| SCHEMBL9291138 | 0.79 | GPR84 (0.56) | LPAR3LPAR2CETPAKR1B1PPARG | |
| SCHEMBL7095448 | 0.79 | LPAR3 (0.71) | LPAR3LPAR2CETPGABBR2GABRR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5153347-A | Phosphonate, phosphinate derivatives useful as antihypertensive agents | E. R. SQUIBB & SONS, INC. (US) | 1992-10-06 | — | — | US | disclosed |